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在刷牙前用酸性物质进行挑战,研究两种脱敏牙膏对牙本质的研磨作用的现场随机试验。

In situ randomised trial investigating abrasive effects of two desensitising toothpastes on dentine with acidic challenge prior to brushing.

机构信息

Applied Clinical Research Group, Department of Oral and Dental Science, University of Bristol, UK.

出版信息

J Dent. 2012 Jan;40(1):77-85. doi: 10.1016/j.jdent.2011.10.010. Epub 2011 Oct 25.

Abstract

OBJECTIVES

To determine if brushing dentine with 2 moderate RDA desensitising toothpastes, results in a significant dentine wear difference and whether this difference continues to be relevant when preceded with an erosive challenge.

METHODS

An in situ, single centre, single blind, randomised, split mouth study, evaluated the difference in abrasion of 2 toothpastes (SFM - Sensodyne Fresh Mint(®) RDA 70; CPHM - Crest Pro-Health Clean Mint(®) RDA 120) in 28 healthy volunteers. Two toothpaste treatments were administered 3×/day, for each of the two 15 day periods, subjects wearing bi-lateral, lower buccal appliances each with 4 dentine sections. A 2 min extra-oral acidic challenge preceded toothbrushing for 2 study arms. Contact profilometry measured samples at baseline, days 5, 10 and 15.

RESULTS

Brushing with SFM was significantly less abrasive than brushing with CPHM at all time points, with or without a preceding acidic challenge (p<0.0001). The additional dentine loss arising from the erosive challenge prior to brushing with each paste was linear with time and independent of abrasive effect.

CONCLUSIONS

The desensiting toothpastes' RDA, directly related to dentine loss with toothbrushing. An acidic challenge prior to brushing did not negate the benefits of reduced wear from the lower RDA paste compared to the higher RDA paste. When brushing eroded dentine, the additional wear appeared independent of abrasive effect. Dentine hypersensitivity sufferers should be recommended to use a low-moderate RDA toothpaste, not to brush more than 2×/day and not immediately following an acidic challenge.

摘要

目的

确定使用两种中度 RDA 脱敏牙膏刷牙是否会导致牙本质磨损有显著差异,以及在进行侵蚀性挑战之前,这种差异是否仍然相关。

方法

一项在体、单中心、单盲、随机、分口研究,评估了两种牙膏(SFM-Sensodyne Fresh Mint®RDA 70;CPHM-Crest Pro-Health Clean Mint®RDA 120)在 28 名健康志愿者中的磨损差异。两种牙膏处理方案均为每天刷牙 3 次,每个 15 天周期刷牙 2 次,受试者佩戴双侧下颌颊侧器械,每个器械有 4 个牙本质区域。在刷牙前,用 2 分钟的口腔外酸性挑战来预处理 2 个研究组。接触式轮廓仪在基线、第 5 天、第 10 天和第 15 天测量样本。

结果

SFM 刷牙明显比 CPHM 刷牙磨损小,无论是否有先前的酸性挑战,均有显著差异(p<0.0001)。在使用每种牙膏刷牙前进行侵蚀性挑战导致的额外牙本质损失随时间呈线性增加,且与磨损效果无关。

结论

脱敏牙膏的 RDA 直接与刷牙导致的牙本质损失相关。在刷牙前进行酸性挑战并没有消除与高 RDA 牙膏相比,低 RDA 牙膏在降低磨损方面的益处。当刷牙侵蚀牙本质时,额外的磨损似乎与磨损效果无关。牙本质敏感症患者应被建议使用中低 RDA 牙膏,每天刷牙不超过 2 次,且不要在酸性挑战后立即刷牙。

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