用于当前及潜在牙科应用的壳聚糖生物材料。
Chitosan Biomaterials for Current and Potential Dental Applications.
作者信息
Husain Shehriar, Al-Samadani Khalid H, Najeeb Shariq, Zafar Muhammad S, Khurshid Zohaib, Zohaib Sana, Qasim Saad B
机构信息
Department of Dental Materials, College of Dentistry, Jinnah Sindh Medical University, Karachi 75110, Pakistan.
Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah 41311, Saudi Arabia.
出版信息
Materials (Basel). 2017 May 31;10(6):602. doi: 10.3390/ma10060602.
Chitosan (CHS) is a very versatile natural biomaterial that has been explored for a range of bio-dental applications. CHS has numerous favourable properties such as biocompatibility, hydrophilicity, biodegradability, and a broad antibacterial spectrum (covering gram-negative and gram-positive bacteria as well as fungi). In addition, the molecular structure boasts reactive functional groups that provide numerous reaction sites and opportunities for forging electrochemical relationships at the cellular and molecular levels. The unique properties of CHS have attracted materials scientists around the globe to explore it for bio-dental applications. This review aims to highlight and discuss the hype around the development of novel chitosan biomaterials. Utilizing chitosan as a critical additive for the modification and improvement of existing dental materials has also been discussed.
壳聚糖（CHS）是一种用途极为广泛的天然生物材料，已被用于一系列生物牙科应用的探索。壳聚糖具有许多优良特性，如生物相容性、亲水性、生物降解性以及广泛的抗菌谱（涵盖革兰氏阴性菌、革兰氏阳性菌和真菌）。此外，其分子结构拥有反应性官能团，这些官能团提供了众多反应位点以及在细胞和分子水平上建立电化学关系的机会。壳聚糖的独特性能吸引了全球材料科学家对其进行生物牙科应用方面的探索。本综述旨在突出并讨论围绕新型壳聚糖生物材料开发的热潮。还探讨了将壳聚糖用作关键添加剂来改性和改进现有牙科材料的情况。
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