Etiology and Risk Factors for Infectious Keratitis in South Texas.

PURPOSE

To determine the causative organisms and associated risk factors for infectious keratitis in South Texas.

METHODS

This retrospective study was performed at a tertiary teaching hospital system in South Texas. Medical records of all patients who presented with infectious keratitis from 2012 to 2018 were reviewed. Only patients with culture-proven bacterial, fungal, and keratitis were included.

RESULTS

In total, 182 eyes of 181 patients had culture-proven bacterial, fungal, or keratitis. The age of patients ranged from 3 to 93 years, with a mean of 48.3 20.8 years. The most common etiologic agent was bacteria, with 173 bacterial cultures (95.1%) recovered, followed by 13 fungal cultures (7.1%), and 3 cultures (1.6%). Of the 218 bacterial isolates, coagulase-negative was the most common (25.7%), followed by (23.4%), (11.0%), and (7.8%). was the most common fungal isolate (46.2%). The most common risk factors for infectious keratitis included contact lens wear (32.4%), underlying corneal disease (17.6%), trauma (14.3%), and ocular surface disease (13.7%).

CONCLUSIONS

Bacteria are the most common cause of infectious keratitis in this patient population, with coagulase-negative and as the most common isolates. The prevalence of culture-positive fungal keratitis is significantly lower than that of bacterial keratitis. Contact lens wear is the most common risk factor associated with infectious keratitis in South Texas.