Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.
Naturalis Biodiversity Center, Leiden, The Netherlands.
F1000Res. 2020 Feb 24;9:136. doi: 10.12688/f1000research.18236.1. eCollection 2020.
We report on the activities of the 2015 edition of the BioHackathon, an annual event that brings together researchers and developers from around the world to develop tools and technologies that promote the reusability of biological data. We discuss issues surrounding the representation, publication, integration, mining and reuse of biological data and metadata across a wide range of biomedical data types of relevance for the life sciences, including chemistry, genotypes and phenotypes, orthology and phylogeny, proteomics, genomics, glycomics, and metabolomics. We describe our progress to address ongoing challenges to the reusability and reproducibility of research results, and identify outstanding issues that continue to impede the progress of bioinformatics research. We share our perspective on the state of the art, continued challenges, and goals for future research and development for the life sciences Semantic Web.
我们报告了 2015 年生物黑客马拉松的活动情况，这是一项年度活动，汇集了来自世界各地的研究人员和开发人员，以开发促进生物数据可重用性的工具和技术。我们讨论了与生物数据和元数据的表示、发布、集成、挖掘和再利用相关的问题，这些数据和元数据涉及广泛的与生命科学相关的生物医学数据类型，包括化学、基因型和表型、同源和系统发育、蛋白质组学、基因组学、糖组学和代谢组学。我们描述了我们为解决研究结果可重用性和可再现性所面临的持续挑战而取得的进展，并确定了继续阻碍生物信息学研究进展的突出问题。我们分享了我们对生命科学语义网的最新技术、持续挑战以及未来研究和开发目标的看法。
