Williams Cheau, Lamar Madison, Delgado Paula
Colquitt Regional Medical Center, Philadelphia College of Osteopathic Medicine, Medical College of Georgia, Moultrie, GA, USA.
2nd Year Resident at Colquitt Regional Medical Center, Georgia South Family Medicine Residency, Moultrie, GA, USA.
Urol Case Rep. 2020 Apr 3;31:101169. doi: 10.1016/j.eucr.2020.101169. eCollection 2020 Jul.
There are three major recognized histological types for primary urethral carcinoma (PUC). These include transitional cell carcinoma (55%), squamous cell carcinoma (21.5%), and adenocarcinoma (16.4%). However, primary urethral carcinoma still only accounts for approximately less than 1% of all bladder cancers. Current management includes surgery alone or surgery with adjunctive radiotherapy and chemotherapy. Current research suggests that in those cases managed with only surgery, the five-year disease-free survival is only 20-30%; as additional treatment with radiotherapy and chemotherapy is new recommendation, there is no published statistical data to suggest outcomes, only current clinical observation.
原发性尿道癌（PUC）有三种主要公认的组织学类型。这些包括移行细胞癌（55%）、鳞状细胞癌（21.5%）和腺癌（16.4%）。然而，原发性尿道癌仍仅占所有膀胱癌的约1%以下。目前的治疗方法包括单纯手术或手术联合辅助放疗和化疗。目前的研究表明，在仅接受手术治疗的病例中，五年无病生存率仅为20%-30%；由于放疗和化疗作为新的辅助治疗方法，尚无已发表的统计数据表明其疗效，只有当前的临床观察结果。
