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与溃疡性结肠炎相关的阑尾腺癌

Appendiceal Adenocarcinoma Associated With Ulcerative Colitis.

作者信息

Nehme Fredy, Schneider Ashley, Hamid Fadi

机构信息

Department of Gastroenterology and Hepatology, University of Missouri Kansas City, Kansas City, MO.

MAWD Pathology, Kansas City, MO.

出版信息

ACG Case Rep J. 2019 Nov 25;6(11):e00255. doi: 10.14309/crj.0000000000000255. eCollection 2019 Nov.

DOI:10.14309/crj.0000000000000255
PMID:32309470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7145221/
Abstract

Ulcerative colitis (UC) is a known risk factor for colorectal cancer, but the association between UC and appendiceal adenocarcinoma remains rare. We present a 42-year-old patient with long-standing UC who presented with acute appendicitis shortly after a routine colonoscopy. Histopathological examination revealed moderately differentiated appendiceal adenocarcinoma. The recognition of appendiceal cancer as a complication of long-standing UC warrants increased clinical awareness.

摘要

溃疡性结肠炎（UC）是结直肠癌的已知危险因素，但UC与阑尾腺癌之间的关联仍然罕见。我们报告一名42岁患有长期UC的患者，在常规结肠镜检查后不久出现急性阑尾炎。组织病理学检查显示为中分化阑尾腺癌。认识到阑尾癌是长期UC的一种并发症，需要提高临床意识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/179b7109c5bf/ac9-6-e00255-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/f8b32c91dce8/ac9-6-e00255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/50465c00982b/ac9-6-e00255-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/4eda0d198f31/ac9-6-e00255-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/179b7109c5bf/ac9-6-e00255-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/f8b32c91dce8/ac9-6-e00255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/50465c00982b/ac9-6-e00255-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/4eda0d198f31/ac9-6-e00255-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57be/7145221/179b7109c5bf/ac9-6-e00255-g004.jpg

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本文引用的文献

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Association Between Indefinite Dysplasia and Advanced Neoplasia in Patients With Inflammatory Bowel Diseases Undergoing Surveillance.炎症性肠病患者接受监测时，不确定型发育异常与高级别肿瘤的相关性。
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一例阑尾腺癌合并溃疡性结肠炎
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Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele: importance of inflammation in the appendiceal orifice related to UC.溃疡性结肠炎与阑尾黏液囊肿原位腺癌之间可能存在的联系：与溃疡性结肠炎相关的阑尾开口处炎症的重要性。
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