Villanueva Saenz E, Pérez-Aguirre J, Belmonte M C, Martínez P H M, Márquez R M L, Carranza R J M
Colorectal Surgery Department, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, México DF, México.
Tech Coloproctol. 2006 Mar;10(1):54-6. doi: 10.1007/s10151-006-0252-7. Epub 2006 Mar 15.
Ulcerative colitis (UC) represents a risk factor for colorectal cancer, but the association between UC and appendix cancer is uncommon. A 60-year-old woman with a 5-year history of UC initially received medical treatment with mesalazine and prednisone with no satisfactory response; therefore surgery was indicated. The procedure was a total intersphincteric proctocolectomy with ileostomy. Histopathological analysis indicated adenocarcinoma from the cecal appendix, and chronic-active ulcerative colitis of the colon. In conclusion, surgeons and pathologists should examine every surgical specimen from patients with UC because of the possibility, although remote, of a neoplasic pathology. The appendix adenocarcinoma and ulcerative colitis may or may not be associated, same as colon cancer in patients with UC.
溃疡性结肠炎（UC）是结直肠癌的一个危险因素，但UC与阑尾癌之间的关联并不常见。一名有5年UC病史的60岁女性最初接受美沙拉嗪和泼尼松药物治疗，效果不佳；因此，建议进行手术。手术方式为全括约肌间直肠结肠切除术并回肠造口术。组织病理学分析显示盲肠阑尾腺癌以及结肠慢性活动性溃疡性结肠炎。总之，外科医生和病理学家应检查UC患者的每一个手术标本，因为尽管可能性很小，但仍有可能存在肿瘤性病理改变。阑尾腺癌与溃疡性结肠炎可能有关，也可能无关，这与UC患者的结肠癌情况相同。
