丁螺环酮用于治疗伴有胃排空加速的功能性消化不良。
Buspirone for the Management of Functional Dyspepsia With Rapid Gastric Emptying.
作者信息
Radetic Mark, Gabbard Scott
机构信息
Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
Department of Gastroenterology, Hepatology, & Nutrition Cleveland Clinic, Cleveland, OH.
出版信息
ACG Case Rep J. 2019 Nov 26;6(11):e00280. doi: 10.14309/crj.0000000000000280. eCollection 2019 Nov.
Functional dyspepsia is characterized by a constellation of upper gastrointestinal symptoms consisting of epigastric pain and burning, early satiety, and postprandial fullness-all in the absence of any explanatory organic gastrointestinal pathology. Treatment options for the condition are limited, in part, because of the incomplete understanding of the pathophysiology of the disorder. A subset of patients diagnosed with functional dyspepsia are subsequently found to have rapid gastric emptying on gastric emptying scintigraphy. The significance of this finding is unknown but provides a potential therapeutic target. This case report describes functional dyspepsia with rapid gastric emptying responsive to treatment with buspirone.
功能性消化不良的特征是一系列上消化道症状，包括上腹部疼痛和烧灼感、早饱感以及餐后饱胀感，而所有这些症状均不存在任何可解释的器质性胃肠病变。该病症的治疗选择有限，部分原因是对该疾病的病理生理学认识不完整。一部分被诊断为功能性消化不良的患者随后在胃排空闪烁扫描中被发现胃排空迅速。这一发现的意义尚不清楚，但提供了一个潜在的治疗靶点。本病例报告描述了对丁螺环酮治疗有反应的伴有胃排空迅速的功能性消化不良。
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