Dehghani Alamtaj Samsami, Homayouni Kaynoosh, Kanannejad Zahra, Kanannejad Zeinab
Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Obstetrics and Gynecology, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Reprod Biomed. 2020 Mar 29;18(3):209-214. doi: 10.18502/ijrm.v18i3.6719. eCollection 2020 Mar.
Acupuncture is an adjunct therapy to support infertile women received in vitro fertilization (IVF) treatment; however, the efficacy of this approach needs more evaluation.
This randomized clinical trial (RCT) study aimed to evaluate the influence of acupuncture on reproductive outcomes in women undergoing IVF treatment.
The study was carried out on 186 participants who had undergone IVF treatment in the Mother and Child Hospital between September 2015 and February 2016. Subjects were randomly divided into three groups: Acupuncture 25 min before embryo transfer (ET) (ACU1 group, n = 62), acupuncture 25 min before and after ET (ACU2 group, n = 62), and ET without acupuncture (control group, n = 62). Pregnancy rates (biochemical, clinical, and ongoing) were evaluated and compared between groups.
There were significant differences between the ACU1 group and the control group regarding biochemical (p = 0.005), clinical (p = 0.006), and ongoing (p = 0.007) pregnancies. Also, our results showed that two-session acupuncture (ACU2) lead to a significant reduction in frequency of biochemical (p = 0.002), clinical (p = 0.003), and ongoing (p = 0.01) pregnancy rates when compared to the one-session acupuncture (ACU1). No significant difference was found between the ACU2 and control groups regarding the aforementioned terms (p = 0.50).
Acupuncture 25 min before ET significantly increased the IVF outcomes in women undergoing IVF compared with no acupuncture. Repeating acupuncture 25 min after ET did not improve the IVF outcome.
针灸是辅助接受体外受精（IVF）治疗的不孕女性的一种疗法；然而，这种方法的疗效需要更多评估。
这项随机临床试验（RCT）旨在评估针灸对接受IVF治疗女性生殖结局的影响。
该研究对2015年9月至2016年2月期间在妇幼医院接受IVF治疗的186名参与者进行。受试者被随机分为三组：胚胎移植（ET）前25分钟进行针灸（ACU1组，n = 62），ET前后25分钟均进行针灸（ACU2组，n = 62），以及不进行针灸的ET组（对照组，n = 62）。评估并比较各组之间的妊娠率（生化妊娠、临床妊娠和持续妊娠）。
ACU1组与对照组在生化妊娠（p = 0.005）、临床妊娠（p = 0.006）和持续妊娠（p = 0.007）方面存在显著差异。此外，我们的结果表明，与单次针灸（ACU1）相比，两次针灸（ACU2）导致生化妊娠（p = 0.002）、临床妊娠（p = 0.003）和持续妊娠（p = 0.01）率的频率显著降低。ACU2组与对照组在上述方面未发现显著差异（p = 0.50）。
与不进行针灸相比，ET前25分钟进行针灸显著提高了接受IVF治疗女性的IVF结局。ET后25分钟重复进行针灸并未改善IVF结局。
