马粪便微生物群移植：当前知识、拟议指南及未来方向。
Equine faecal microbiota transplant: Current knowledge, proposed guidelines and future directions.
作者信息
Mullen K R, Yasuda K, Divers T J, Weese J S
机构信息
Littleton Equine Medical Center Colorado USA.
Harvard T.H. Chan School of Public Health Boston Massachusetts USA.
出版信息
Equine Vet Educ. 2018 Mar;30(3):151-160. doi: 10.1111/eve.12559. Epub 2016 Feb 28.
Abstract
While certainly not a novel concept, faecal microbiota transplant (FMT) has recently garnered renewed interest in veterinary medicine due to its remarkable success in treating recurrent infection (CDI) in man. There is a dearth of information on indications and efficacy of FMT for the treatment of gastrointestinal disorders in the horse; however, based on evidence in man and other veterinary species, and anecdotal reports in horses, FMT may be a useful treatment for selected cases of acute and chronic diarrhoea and inflammatory bowel disease (IBD) in the horse. In the absence of evidence, expert opinion is offered on case selection and FMT procedure. More research is needed to explore the efficacy, indications and optimal preparation, storage and delivery of FMT to horses.
摘要
虽然粪便微生物群移植（FMT）肯定不是一个新概念，但由于其在治疗人类复发性艰难梭菌感染（CDI）方面取得了显著成功，最近在兽医学中重新引起了人们的兴趣。关于FMT治疗马匹胃肠道疾病的适应症和疗效的信息匮乏；然而，根据人类和其他兽医物种的证据以及马匹的轶事报道，FMT可能是治疗马匹某些急性和慢性腹泻及炎症性肠病（IBD）病例的有效方法。在缺乏证据的情况下，就病例选择和FMT程序提供了专家意见。需要更多的研究来探索FMT对马匹的疗效、适应症以及最佳制备、储存和给药方式。
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