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天然保健品中的汞作为膜性肾病的一个病因。

Mercury in natural health products as a cause of membranous nephropathy.

作者信息

Tanner Stephen, Sharma Vivek, Jebakumar Deborah, Narayanan Mohanram, Rao Arundhati

机构信息

Department of Nephrology, Baylor Scott & WhiteTempleTexas.

Department of Pathology, Baylor Scott & WhiteTempleTexas.

出版信息

Proc (Bayl Univ Med Cent). 2020 Jan 30;33(2):243-245. doi: 10.1080/08998280.2020.1719782. eCollection 2020 Apr.

Abstract

Membranous nephropathy is a glomerular disease characterized by diffuse subepithelial immune complex deposition along the glomerular basement membrane. It can be both primary and secondary to malignancy and various drugs. An emerging area of concern is heavy metal exposure from use of largely unregulated natural health products. Here we present a case of biopsy-proven membranous nephropathy due to natural health products contaminated with mercury.

摘要

膜性肾病是一种肾小球疾病,其特征是沿肾小球基底膜有弥漫性上皮下免疫复合物沉积。它既可以是原发性的,也可以继发于恶性肿瘤和各种药物。一个新出现的令人担忧的领域是使用基本未受监管的天然保健品导致的重金属暴露。在此,我们报告一例经活检证实的因被汞污染的天然保健品导致的膜性肾病病例。

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Mercury in natural health products as a cause of membranous nephropathy.天然保健品中的汞作为膜性肾病的一个病因。
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本文引用的文献

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Membranous Nephropathy: Approaches to Treatment.膜性肾病:治疗方法。
Am J Nephrol. 2018;47 Suppl 1:30-42. doi: 10.1159/000481635. Epub 2018 May 31.
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Drug-induced glomerular disease: immune-mediated injury.药物性肾小球疾病:免疫介导性损伤。
Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1300-10. doi: 10.2215/CJN.01910215. Epub 2015 Jun 19.
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Arsenic-mediated nephrotoxicity.砷介导的肾毒性。
Ren Fail. 2015 May;37(4):542-7. doi: 10.3109/0886022X.2015.1013419. Epub 2015 Feb 23.
7
Mercury-induced membranous nephropathy: clinical and pathological features.汞诱导的膜性肾病:临床和病理特征。
Clin J Am Soc Nephrol. 2010 Mar;5(3):439-44. doi: 10.2215/CJN.07571009. Epub 2010 Jan 14.

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