Kalogeropoulos Petros, Sardeli Aggeliki, Liapis George, Giannakopoulos Panagiotis, Lionaki Sophia
Department of Nephrology, Second Department of Propaedeutic Internal Medicine, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, GRC.
First Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, GRC.
Cureus. 2024 Jan 10;16(1):e52029. doi: 10.7759/cureus.52029. eCollection 2024 Jan.
Heavy metals are found in many products used in everyday life. In addition, many workers are exposed to higher concentrations of such metals in their work environment. Many of these metals may cause toxic effects in humans and there are many reports relating them to the occurrence of kidney disorders such as nephrotic syndrome. In this study, we present a case of a 38-year-old woman with nephrotic syndrome suspected to be related to heavy metal toxicity, after ruling out all other secondary causes. At the same time, she proved refractory to multiple therapies. Furthermore, a related literature review regarding the occurrence of nephrotic syndrome in patients with heavy metal exposure is presented with emphasis on the importance of considering them as a secondary cause, especially in cases that appear resistant to treatment.
重金属存在于许多日常生活用品中。此外，许多工人在工作环境中接触到更高浓度的此类金属。这些金属中的许多可能会对人类产生毒性作用，并且有许多报告将它们与肾脏疾病如肾病综合征的发生联系起来。在本研究中，我们报告了一例38岁患有肾病综合征的女性病例，在排除所有其他继发原因后，怀疑与重金属中毒有关。同时，她对多种治疗均无效。此外，本文还对重金属暴露患者中肾病综合征的发生进行了相关文献综述，强调了将其视为继发原因的重要性，特别是在那些似乎对治疗有抵抗性的病例中。
