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成人脊柱畸形进展的自然史:一项影像学分析

The Natural History of Progression in Adult Spinal Deformity: A Radiographic Analysis.

作者信息

Faraj Sayf S A, Te Hennepe Niek, van Hooff Miranda L, Pouw Martin, de Kleuver Marinus, Spruit Maarten

机构信息

Radboud University Medical Center, Department of Orthopedics, Nijmegen, the Netherlands.

Sint Maartenskliniek, Department of Orthopaedic Surgery, Nijmegen, the Netherlands.

出版信息

Global Spine J. 2020 May;10(3):272-279. doi: 10.1177/2192568219845659. Epub 2019 May 1.

Abstract

STUDY DESIGN

Historical cohort study.

OBJECTIVE

To evaluate progression in the coronal and sagittal planes in nonsurgical patients with adult spinal deformity (ASD).

METHODS

A retrospective analysis of nonsurgical ASD patients between 2005 and 2017 was performed. Magnitude of the coronal and sagittal planes were compared on the day of presentation and at most recent follow-up. Previous reported prognostic factors for progression in the coronal plane, including the direction of scoliosis, curve magnitude, and the position of the intercrest line (passing through L4 or L5 vertebra), were studied.

RESULTS

Fifty-eight patients were included with a mean follow-up of 59.8 ± 34.5 months. Progression in the coronal plane was seen in 72% of patients. Mean Cobb angle on the day of presentation and most recent follow-up was 37.2 ± 14.6° and 40.8° ± 16.5°, respectively. No significant differences were found in curve progression in left- versus right-sided scoliosis (3.3 ± 7.1 vs 3.7 ± 5.4, = .81), Cobb angle <30° versus ≥30° (2.6 ± 5.0 vs 4.3 ± 6.5, = .30), or when the intercrest line passed through L4 rather than L5 vertebra (3.4 ± 5.0° vs 3.8 ± 7.1°, = .79). No significant differences were found in the sagittal plane between presentation and most recent follow-up.

CONCLUSIONS

This is the first study that describes progression in the coronal and sagittal planes in nonsurgical patients with ASD. Previous reported prognostic factors were not confirmed as truly relevant. Although progression appears to occur, large variation exists and these results may not be directly applicable to the individual patient.

摘要

研究设计

历史性队列研究。

目的

评估非手术治疗的成人脊柱畸形(ASD)患者在冠状面和矢状面的进展情况。

方法

对2005年至2017年间非手术治疗的ASD患者进行回顾性分析。比较就诊当天和最近一次随访时冠状面和矢状面的大小。研究先前报道的冠状面进展的预后因素,包括脊柱侧弯方向、侧弯度数以及髂嵴连线(经过L4或L5椎体)的位置。

结果

纳入58例患者,平均随访时间为59.8±34.5个月。72%的患者在冠状面有进展。就诊当天和最近一次随访时的平均Cobb角分别为37.2±14.6°和40.8°±16.5°。左侧与右侧脊柱侧弯的曲线进展无显著差异(3.3±7.1与3.7±5.4,P = 0.81),Cobb角<30°与≥30°的情况无显著差异(2.6±5.0与4.3±6.5,P = 0.30),髂嵴连线经过L4而非L5椎体时也无显著差异(3.4±5.0°与3.8±7.1°,P = 0.79)。就诊时与最近一次随访时在矢状面无显著差异。

结论

这是第一项描述非手术治疗的ASD患者在冠状面和矢状面进展情况的研究。先前报道的预后因素未被证实具有真正的相关性。尽管似乎存在进展,但个体差异较大,这些结果可能无法直接应用于个体患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16e6/7160806/e092e6e8a82f/10.1177_2192568219845659-fig1.jpg

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