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纤维肌痛、干燥综合征与抑郁症:有关联吗?

Fibromyalgia, Sjogren's & depression: linked?

机构信息

Department of Behavior Medicine and Psychiatry, West Virginia University , Morgantown, WV, USA.

Department of Medicine, Division of Rheumatology, West Virginia University , Morgantown, WV, USA.

出版信息

Postgrad Med. 2020 Sep;132(7):575-580. doi: 10.1080/00325481.2020.1758426. Epub 2020 May 20.

DOI:10.1080/00325481.2020.1758426
PMID:32314938
Abstract

Health care has become increasingly fragmented, partly due to advancing medical technology. Patients are often managed by various specialty teams when presenting with symptoms that could be manifestations of different diseases. Approximately one third of them are referred to specialists, at over half for outpatient appointments. Fatigue, pain, depression, dry mouth, headaches, and arthralgia are common complaints and frequently require referral to specialist physicians. Differential diagnoses include fibromyalgia (FM), Sjogren's syndrome (SS), and depression. Evaluations involve various sub-specialist especially physicians like those practicing pain management, rheumatology, and psychiatry. Thresholds for referring vary. Patients sometime feel lost in a 'medical maze'. Disagreement is frequent between specialties regarding management. Each discipline has its own diagnostic and treatment protocols and there is little consensus about shared decision-making. Communication between doctors could improve continuity. There are many differences and similarities in the pathophysiology, symptomatology, diagnosis, and treatment of fibromyalgia, Sjogren's syndrome, and depression. Understanding the associations between fibromyalgia, Sjogren's syndrome and depression should improve clinical outcome via a common holistic approach.

摘要

医疗服务变得越来越碎片化,部分原因是医疗技术的进步。当患者出现可能是不同疾病表现的症状时,通常会由多个专科团队进行管理。其中约有三分之一的患者被转介给专科医生,超过一半的患者是门诊预约。疲劳、疼痛、抑郁、口干、头痛和关节痛是常见的主诉,通常需要转介给专科医生。鉴别诊断包括纤维肌痛(FM)、干燥综合征(SS)和抑郁症。评估涉及各种亚专科医生,尤其是从事疼痛管理、风湿病学和精神病学的医生。转诊的标准不同。患者有时会感到迷失在“医疗迷宫”中。不同专科之间的治疗意见经常存在分歧。每个学科都有自己的诊断和治疗方案,对于共同决策几乎没有共识。医生之间的沟通可以提高连续性。纤维肌痛、干燥综合征和抑郁症在病理生理学、症状学、诊断和治疗方面存在许多差异和相似之处。通过共同的整体方法理解纤维肌痛、干燥综合征和抑郁症之间的关联,应该可以改善临床结果。

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Fibromyalgia, Sjogren's & depression: linked?纤维肌痛、干燥综合征与抑郁症:有关联吗?
Postgrad Med. 2020 Sep;132(7):575-580. doi: 10.1080/00325481.2020.1758426. Epub 2020 May 20.
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[Fibromyalgia and Sjögren syndrome--clinical and methodological aspects].[纤维肌痛与干燥综合征——临床及方法学方面]
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[Fibromyalgia--an artifact?].[纤维肌痛——一种假象?]
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Prevalence and clinical impact of fibromyalgia in patients with primary Sjögren's syndrome.原发性干燥综合征患者中纤维肌痛的患病率及临床影响
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Fatigue and widespread pain in systemic lupus erythematosus and Sjögren's syndrome: symptoms of the inflammatory disease or associated fibromyalgia?系统性红斑狼疮和干燥综合征中的疲劳和广泛疼痛:是炎症性疾病的症状还是相关纤维肌痛症的症状?
Clin Exp Rheumatol. 2012 Nov-Dec;30(6 Suppl 74):117-21. Epub 2012 Dec 14.

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J Pers Med. 2023 Jun 7;13(6):961. doi: 10.3390/jpm13060961.
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Higher Risk for Sjögren's Syndrome in Patients With Fibromyalgia: A Nationwide Population-Based Cohort Study.纤维肌痛患者发生干燥综合征的风险更高:一项全国范围内基于人群的队列研究。
Front Immunol. 2021 Apr 12;12:640618. doi: 10.3389/fimmu.2021.640618. eCollection 2021.
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Application of Salivary Biomarkers in the Diagnosis of Fibromyalgia.唾液生物标志物在纤维肌痛诊断中的应用。
Diagnostics (Basel). 2021 Jan 3;11(1):63. doi: 10.3390/diagnostics11010063.