视神经脊髓炎谱系障碍伴随后发性渗透性脱髓鞘综合征的下颌阵挛
Jaw clonus in neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome.
作者信息
Ghosh Ritwik, Roy Devlina, Dubey Souvik, Lahiri Durjoy, Chatterjee Subhankar, Finsterer Josef
机构信息
Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, India.
Department of Neuromedicine, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research and SSKM Hospital, Kolkata, India.
出版信息
J Family Med Prim Care. 2020 Feb 28;9(2):1209-1211. doi: 10.4103/jfmpc.jfmpc_1117_19. eCollection 2020 Feb.
Jaw clonus, a fascinating, yet uncommon clinical sign, is suggestive of supranuclear lesions of the trigeminal nerve. It has previously been reported in association with amyotrophic lateral sclerosis. Hereby, we report an index case of jaw clonus in a patient of neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome with pseudobulbar palsy due to the involvement of pontine corticobulbar fibres.
下颌阵挛是一种引人关注但并不常见的临床体征，提示三叉神经的核上性病变。此前曾有报道称其与肌萎缩侧索硬化症相关。在此，我们报告一例视神经脊髓炎谱系障碍患者出现下颌阵挛的索引病例，该患者随后因脑桥皮质延髓纤维受累而发生渗透性脱髓鞘综合征并伴有假性球麻痹。
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