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免疫功能正常宿主的棘阿米巴脑炎:两例报告。

Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases.

作者信息

Das Sohini, Gunasekaran Karthik, Ajjampur Sitara S R, Abraham Dilip, George Tina, Janeela M Asisha, Iyadurai Ramya

机构信息

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2020 Feb 28;9(2):1240-1243. doi: 10.4103/jfmpc.jfmpc_1010_19. eCollection 2020 Feb.

DOI:10.4103/jfmpc.jfmpc_1010_19
PMID:32318505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7114032/
Abstract

are ubiquitous free-living amoeba. Acanthamoeba infections cause necrotizing vasculitis, resulting in vessel thrombosis and cerebral infarction. Acanthamoeba CNS infections, though uncommon, are associated with high mortality. Diagnosis is difficult and often delayed. Here, we present two immunocompetent hosts with Acanthamoeba encephalitis with good outcomes.

摘要

棘阿米巴是普遍存在的自由生活阿米巴。棘阿米巴感染会导致坏死性血管炎,进而引发血管血栓形成和脑梗死。棘阿米巴中枢神经系统感染虽不常见,但死亡率很高。诊断困难且常常延误。在此,我们报告两例免疫功能正常的宿主患棘阿米巴脑炎且预后良好的病例。

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