Kelly T M, Jensen R L, Elliott C G, Crapo R O
Division of General Internal Medicine, LDS Hospital, Salt Lake City, Utah.
Respiration. 1988;54(2):73-7. doi: 10.1159/000195504.
Maximum inspiratory and expiratory pressures were measured at residual volume, total lung capacity, and functional residual capacity in 45 morbidly obese patients who on average weighed 183% of their predicted weights. The pressures were compared to determinations made in 25 subjects of similar age whose mean weight was 99% of predicted. For both men and women, pressures generated by control subjects tended to be higher than those produced by obese patients but the differences were not statistically significant. The mean vital capacity and total lung capacity were also similar in the 2 subject groups. The results indicate that despite working constantly against a less compliant chest wall, obese patients do not increase their capacity to generate maximal respiratory pressures.
对45名病态肥胖患者在残气量、肺总量和功能残气量时的最大吸气和呼气压力进行了测量，这些患者的平均体重为预测体重的183%。将这些压力与25名年龄相仿、平均体重为预测体重99%的受试者的测量结果进行了比较。对于男性和女性，对照组受试者产生的压力往往高于肥胖患者产生的压力，但差异无统计学意义。两个受试者组的平均肺活量和肺总量也相似。结果表明，尽管肥胖患者始终要对抗顺应性较差的胸壁，但他们产生最大呼吸压力的能力并未增加。
