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下颌骨广泛硬化性牙源性癌:病例报告及文献复习。

An extensive sclerosing odontogenic carcinoma in mandible: a case report and literature review.

机构信息

Department of Dentomaxillofacial Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.

Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.

出版信息

Dentomaxillofac Radiol. 2020 Sep 1;49(6):20190426. doi: 10.1259/dmfr.20190426. Epub 2020 May 7.

Abstract

Sclerosing odontogenic carcinoma (SOC) is a primary intraosseous carcinoma of the jaw that was listed as a separate entity for the first time in the latest version of the World Health Organization classification of Head and Neck Tumors (2017). In this report, we present a case of SOC involving a circuitous diagnostic process because of the inadequately detailed biopsy findings and inherent impression based on the imaging manifestations. Through an extensive literature review, the histopathological and immunohistochemical features of the disease were briefly summarized. Radiological findings of SOC have been characterized in detail, and an imaging classification scheme has been proposed to further discuss the diversity of radiographic features. Due to the rarity of the disease, a comprehensive understanding of SOC is needed, and close collaboration between clinicians, radiologists, and pathologists is crucial to avoid misdiagnosis.

摘要

硬化性牙源性癌(SOC)是一种原发性颌骨内源性癌,在最新版《世界卫生组织头颈部肿瘤分类》(2017 年)中首次被列为独立实体。本报告介绍了一例 SOC 病例,由于活检结果不够详细以及基于影像学表现的固有印象,导致诊断过程曲折。通过广泛的文献复习,简要总结了该病的组织病理学和免疫组织化学特征。详细描述了 SOC 的放射学表现,并提出了一种影像学分类方案,以进一步讨论放射学特征的多样性。由于该病罕见,需要全面了解 SOC,临床医生、放射科医生和病理科医生之间的密切合作对于避免误诊至关重要。

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