Ávila Daniele Mara da Silva, Zanatta Rayssa Ferreira, Scaramucci Tais, Aoki Idalina Vieira, Torres Carlos Rocha Gomes, Borges Alessandra Bühler
Department of Restorative Dentistry, Institute of Science and Technology, São Paulo State University-UNESP, São Paulo, Brazil.
Department of Restorative Dentistry, Institute of Science and Technology, São Paulo State University-UNESP, São Paulo, Brazil; Department of Restorative Dentistry, Dental School, University of Taubaté, Taubaté, Brazil.
J Dent. 2020 Oct;101:103347. doi: 10.1016/j.jdent.2020.103347. Epub 2020 Apr 19.
To evaluate if the bioadhesive polymer (Carbopol 980) could potentiate the protective effect of sodium fluoride with stannous chloride (FS) solution on the control of enamel erosive wear.
Cylindrical bovine enamel specimens were polished and randomly allocated into three groups (n = 60): FS (500 ppm F +800 ppm Sn - positive control), FS + Carbopol (0.1% Carbopol), and ultrapure water (negative control). A randomized double-blind cross-over in situ model with three phases was used. In each phase, volunteers (n = 15) used a palatal appliance containing 4 specimens: two were submitted to an erosion model (2 h of pellicle formation; immersion in 1% citric acid, pH 2.3, for 5 min, 4x/day; 1 h intervals of saliva exposure; and treatment with the test solutions for 1 min, 2x/day). Besides erosion, the other two specimens were also subjected to abrasion (2x/day, 15 s) with active electric toothbrush, before the treatment with the solutions. After 5 days, enamel surface loss (μm) was evaluated by profilometry. Data were analyzed by two-way RM-ANOVA and Tukey tests (5%).
There were significant differences for both challenge and treatment factors. Erosion/abrasion challenge resulted in significantly higher enamel loss than erosion only (p < 0.05). The surface loss values for the erosion/remineralization model were (means ± SL): C = 14.7 ± 5.8b; FS = 9.0 ± 7.5ab; FS + Carbopol = 5.9 ± 3.8a; and for erosion/abrasion: C = 26.6 ± 10.1c; FS = 15.0 ± 8.8b; FS + Carbopol = 12.3 ± 7.9ab.
The association of Carbopol to the FS solution significantly protected the enamel against erosive wear, but it was not significantly superior to FS only.
Under highly erosive and abrasive conditions, rinsing with solutions containing sodium fluoride plus stannous chloride, associated or not with the Carbopol polymer, is an effective approach to control enamel erosive wear.
评估生物黏附性聚合物（卡波姆980）是否能增强氟化钠与氯化亚锡（FS）溶液对控制牙釉质侵蚀性磨损的保护作用。
将圆柱形牛牙釉质标本打磨后随机分为三组（n = 60）：FS组（500 ppm氟 + 800 ppm锡 - 阳性对照）、FS + 卡波姆组（0.1%卡波姆）和超纯水组（阴性对照）。采用具有三个阶段的随机双盲交叉原位模型。在每个阶段，志愿者（n = 15）使用一个含有4个标本的腭部矫治器：其中两个标本接受侵蚀模型（2小时形成 pellicle；浸入1%柠檬酸，pH 2.3，5分钟，每天4次；唾液暴露间隔1小时；并用测试溶液处理1分钟，每天2次）。除侵蚀外，另外两个标本在溶液处理前还用电动牙刷进行磨损（每天2次，15秒）。5天后，通过轮廓仪评估牙釉质表面损失（μm）。数据采用双向重复测量方差分析和Tukey检验（5%）进行分析。
挑战因素和处理因素均存在显著差异。侵蚀/磨损挑战导致的牙釉质损失显著高于仅侵蚀（p < 0.05）。侵蚀/再矿化模型的表面损失值为（平均值±标准差）：对照组 = 14.7 ± 5.8b；FS组 = 9.0 ± 7.5ab；FS + 卡波姆组 = 5.9 ± 3.8a；侵蚀/磨损模型的表面损失值为：对照组 = 26.6 ± 10.1c；FS组 = 15.0 ± 8.8b；FS + 卡波姆组 = 12.3 ± 7.9ab。
卡波姆与FS溶液联合使用能显著保护牙釉质免受侵蚀性磨损，但并不显著优于单独使用FS。
在高度侵蚀性和磨蚀性条件下，用含氟化钠加氯化亚锡的溶液冲洗，无论是否与卡波姆聚合物联合使用，都是控制牙釉质侵蚀性磨损的有效方法。
