Department of Ophthalmology, Ehime University Graduate School of Medicine , Shitsukawa, Toon, Ehime, Japan.
Department of Ophthalmology, Saiseikai Matsuyama Hospital , Matsuyama, Ehime, Japan.
Curr Eye Res. 2020 Dec;45(12):1590-1597. doi: 10.1080/02713683.2020.1760305. Epub 2020 May 3.
: To determine the quality of life (QOL) and quality of vision (QOV) of patients who developed and did not develop dry eye disease (DED) after nasolacrimal duct obstruction (NLDO) treatment. : This was a retrospective nonrandomized observational study of 91 patients diagnosed with unilateral NLDO. The subjects underwent lacrimal stent insertion, and the stent was removed after 10-12 weeks. The QOL and QOV of the patients were examined preoperatively and at 6 months after the stent was removed. The postoperative outcomes were assessed subjectively with the Glasgow Benefit Inventory (GBI) questionnaire and an ocular specific questionnaire of 6 symptoms. The best-corrected visual acuity, functional visual acuity, and dry eye scores were also determined. : Of the 91 eyes, 19 eyes (20.9%) were diagnosed with DED (D group) and 72 were not (N group). Five of the 6 symptoms improved in the N group, while only 3 symptoms improved in the D group without blurred vision. For the GBI questionnaire, the social support and physical health scores were significantly higher in the N group than in the D group. The functional visual acuity improved significantly in the N group but not significantly in the D group. : Patients who develop DED after treatments for NLDO may not have an improvement of their QOL or QOV. Therefore, careful dry eye assessments are important before treatments for NLDO.
评估鼻泪管阻塞(NLDO)治疗后发生和未发生干眼(DED)的患者的生活质量(QOL)和视力质量(QOV)。
这是一项回顾性非随机观察研究,纳入了 91 例单侧 NLDO 患者。所有患者均接受了泪道支架植入术,10-12 周后取出支架。在术前和支架取出后 6 个月评估患者的 QOL 和 QOV。术后结局通过格拉斯哥获益量表(GBI)问卷和 6 项眼部症状的眼部特定问卷进行主观评估。同时还评估了最佳矫正视力、功能性视力和干眼评分。
91 只眼中,19 只眼(20.9%)诊断为 DED(D 组),72 只眼未诊断为 DED(N 组)。N 组的 6 项眼部症状中有 5 项得到改善,而 D 组中除视力模糊外,仅有 3 项症状得到改善。在 GBI 问卷中,N 组的社会支持和身体健康评分明显高于 D 组。N 组的功能性视力明显改善,但 D 组无明显改善。
NLDO 治疗后发生 DED 的患者,其 QOL 或 QOV 可能不会得到改善。因此,在进行 NLDO 治疗前,应仔细评估干眼情况。