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与阿米卡星脂质体吸入混悬液相关的呼吸不良事件的临床管理:一项患者调查结果

Clinical Management of Respiratory Adverse Events Associated With Amikacin Liposome Inhalation Suspension: Results From a Patient Survey.

作者信息

Swenson Colin, Lapinel Nicole C, Ali Juzar

机构信息

Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Emory University, Atlanta, Georgia, USA.

Section of Pulmonary/Critical Care Medicine & Allergy/Immunology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.

出版信息

Open Forum Infect Dis. 2020 Mar 2;7(4):ofaa079. doi: 10.1093/ofid/ofaa079. eCollection 2020 Apr.

DOI:10.1093/ofid/ofaa079
PMID:32322600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7162617/
Abstract

Patients with complex lung disease treated with amikacin liposome inhalation suspension (ALIS) at 2 clinics in the United States were surveyed to assess the frequency and management of ALIS-associated respiratory adverse events. Most respondents experienced these events, but management through physician-guided measures (eg, bronchodilator use, oral rinses, and/or temporary dosing adjustments) resulted in symptomatic improvement.

摘要

在美国两家诊所接受阿米卡星脂质体吸入混悬液(ALIS)治疗的复杂肺部疾病患者接受了调查,以评估与ALIS相关的呼吸道不良事件的发生频率和处理情况。大多数受访者经历过这些事件,但通过医生指导的措施(如使用支气管扩张剂、口腔冲洗和/或临时调整剂量)进行处理后症状得到改善。

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2
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3
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BMJ Open Respir Res. 2017 Oct 19;4(1):e000242. doi: 10.1136/bmjresp-2017-000242. eCollection 2017.
4
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5
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7
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8
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Am J Respir Crit Care Med. 2017 Mar 15;195(6):814-823. doi: 10.1164/rccm.201604-0700OC.
9
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Pediatr Pulmonol. 2016 Feb;51(2):115-32. doi: 10.1002/ppul.23304. Epub 2015 Sep 29.
10
Epidemiology of human pulmonary infection with nontuberculous mycobacteria: a review.人类非结核分枝杆菌肺部感染的流行病学:综述
Clin Chest Med. 2015 Mar;36(1):13-34. doi: 10.1016/j.ccm.2014.10.002. Epub 2014 Nov 6.