Laboratory of Collective Health Physiotherapy, Department of Physiotherapy, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Postgraduate Program of Physiotherapy, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Arch Gerontol Geriatr. 2020 Jul-Aug;89:104061. doi: 10.1016/j.archger.2020.104061. Epub 2020 Apr 13.
The aim of this study was to verify if the association of hypertension and diabetes mellitus could lead to the differences on cardiorespiratory fitness and lipid profile in older adults.
40 older adults were divided into two groups: Hypertensive (HTN) and Hypertensive-diabetic (HTN + T2DM). Maximum exercise test on a treadmill was conducted. Lipid profiles assessment was conducted before and after exercise. The cardiorespiratory fitness (CRF) variables were peak oxygen consumption (VO), time to reach peak oxygen consumption (TVO), carbon dioxide ventilatory equivalent (VE/VCO) and carbon dioxide production (VCO). To test intergroup and intragroup analyses independent and paired t-tests were used before and after acute exercise. Multiple linear regression was performed to test the influence of coexistence of HTN and T2DM on CRF.
CRF measures such as VO (β = -3.90), VCO (β = -3.87) and TVO (β= -115.79) were significantly (p-value <0.01) lower in HTN + T2DM group. After acute exercise, there was an increase in the levels of lipid profile variables, however without differences between groups.
HTN + T2DM older adults had poorer CRF. Acute changes in lipemia were similar in both groups.
本研究旨在验证高血压和糖尿病的合并是否会导致老年人在心肺功能和血脂谱方面存在差异。
将 40 名老年人分为两组：高血压组（HTN）和高血压合并 2 型糖尿病组（HTN+T2DM）。在跑步机上进行最大运动测试。在运动前后进行血脂谱评估。心肺功能（CRF）变量包括最大摄氧量（VO）、达到最大摄氧量的时间（TVO）、二氧化碳通气当量（VE/VCO）和二氧化碳产生量（VCO）。为了测试组间和组内差异，在急性运动前后使用独立和配对 t 检验进行分析。进行多元线性回归分析以测试 HTN 和 T2DM 共存对 CRF 的影响。
HTN+T2DM 组的 CRF 测量值，如 VO（β=-3.90）、VCO（β=-3.87）和 TVO（β=-115.79）显著降低（p 值<0.01）。急性运动后，血脂谱变量水平有所升高，但两组之间没有差异。
HTN+T2DM 的老年人心肺功能较差。两组急性脂血症变化相似。
