Casari Bariani Giuliocesare, Zhou Lan, Poggesi Simone, Mittapalli Rakesh, Manzano Marisa, Ionescu Rodica Elena
Laboratoire Lumière, Nanomatériaux et Nanotechnologies - L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France.
Dipartimento di Scienze Agroalimentari, Ambientali e Animali (DI4A), Università degli Studi di Udine, Via Sondrio 2/A, 33,100 Udine, Italy.
Nanomaterials (Basel). 2020 Apr 20;10(4):790. doi: 10.3390/nano10040790.
Celiac diseases are a group of gluten ingestion-correlated pathologies that are widespread and, in some cases, very dangerous for human health. The only effective treatment is the elimination of gluten from the diet throughout life. Nowadays, the food industries are very interested in cheap, easy-to-handle methods for detecting gluten in food, in order to provide their consumers with safe and high-quality food. Here, for the first time, the manufacture of controlled micropatterns of annealed gold nanoislands (AuNIs) on a single QCM crystal (QCM-color) and their biofunctionalization for the specific detection of traces of gliadin is reported. In addition, the modified quartz crystal with a TEM grid and 30 nm Au (Q-TEM grid crystal) is proposed as an acoustic sensitive biosensing platform for the rapid screening of the gliadin content in real food products.
乳糜泻是一组与摄入麸质相关的病症，这类病症普遍存在，在某些情况下对人体健康危害极大。唯一有效的治疗方法是终身从饮食中剔除麸质。如今，食品行业对检测食品中麸质的廉价、易于操作的方法非常感兴趣，以便为消费者提供安全且高质量的食品。在此，首次报道了在单个石英晶体微天平（QCM）晶体上制造退火金纳米岛（AuNIs）的可控微图案（QCM-颜色）及其生物功能化，用于特异性检测痕量麦醇溶蛋白。此外，提出了带有透射电子显微镜（TEM）网格和30纳米金的改性石英晶体（Q-TEM网格晶体）作为一种声学灵敏生物传感平台，用于快速筛查实际食品中的麦醇溶蛋白含量。
