Nishinaka Anri, Nitta Koki, Seki Takashi, Hara Hideaki, Shimazawa Masamitsu
Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
Department of Internal Medicine & Rehabilitation Science, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Evid Based Complement Alternat Med. 2020 Apr 6;2020:6405471. doi: 10.1155/2020/6405471. eCollection 2020.
Acupuncture is used to treat a wide variety of eye diseases, although there is little evidence about the effects of acupuncture treatment and the mechanisms responsible for them. Foot acupuncture treatment has effects in both mice and humans. The purpose of this study was to investigate the effects of acupuncture treatment on ocular blood flow in mice. We evaluated ocular blood flow in C57BL/6J mice after foot acupuncture treatment using laser speckle flowgraphy. The mean blur rate, which is an index of blood flow velocity, was increased in the foot acupuncture group. Our results showed that, after 3 minutes' foot acupuncture, ocular blood flow was significantly increased in both the blood vessels and tissue of the eye in C57BL/6J mice. Thus, performing acupuncture in mice might help to determine its effects. Furthermore, acupuncture is considered to be a possible treatment for ocular disease.
针灸被用于治疗多种眼部疾病，尽管关于针灸治疗的效果及其作用机制的证据很少。足部针灸治疗在小鼠和人类中均有效果。本研究的目的是调查针灸治疗对小鼠眼部血流的影响。我们使用激光散斑血流图评估了C57BL/6J小鼠足部针灸治疗后的眼部血流。作为血流速度指标的平均模糊率在足部针灸组中有所增加。我们的结果表明，在C57BL/6J小鼠中，进行3分钟的足部针灸后，眼部血管和组织中的眼部血流均显著增加。因此，在小鼠身上进行针灸可能有助于确定其效果。此外，针灸被认为是一种可能的眼部疾病治疗方法。
