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基于精油的抗菌电纺纳米纤维垫在生物医学中的应用。

Antimicrobial Electrospun Nanofibrous Mat Based on Essential Oils for Biomedical Applications.

机构信息

Department of Mechanical Design Engineering, Graduate School, Chonbuk National University, Jeonju City, KS004, Republic of Korea.

Department of Bionanosystem Engineering, Chonbuk National University, Jeonju City, KS004, Republic of Korea.

出版信息

J Nanosci Nanotechnol. 2020 Sep 1;20(9):5376-5380. doi: 10.1166/jnn.2020.17669.

Abstract

Polyurethane (PU) nanofibers containing three different essential oils (teatree, cinnamon bark, clove) were produced by electrospinning method. Morphology of the electrospun nanofibrous was studied using Field Emission Scanning Electron Microscope (FE-SEM). We were studying to reveal that different concentration of essential oil display different mechanical properties for the nanofibrous mat. The antibacterial properties of the nanofibrous loaded with the essential oil were studied quantitatively and qualitatively using three strains (). The antibacterial evaluation showed higher antibacterial activity for nanofibrous loaded with essential oil compares to control sample. cell culture were proceed to confirm biocompatibility of the nanofibrous contained essential oils. In this study, we present a comparison of the samples for each of the experiment based on the derived test items and test methods. The results of this study demonstrate that the proposed nanofibrous mat loaded with essential oil will be a promising future material for different biomedical applications.

摘要

通过静电纺丝法制备了含有三种不同精油(茶树、肉桂皮、丁香)的聚氨酯(PU)纳米纤维。使用场发射扫描电子显微镜(FE-SEM)研究了电纺纳米纤维的形态。我们研究揭示了不同浓度的精油对纳米纤维垫显示出不同的机械性能。使用三种菌株()定量和定性研究了负载精油的纳米纤维的抗菌性能。抗菌评价表明,负载精油的纳米纤维的抗菌活性高于对照样品。进行细胞培养以确认含精油的纳米纤维的生物相容性。在这项研究中,我们根据得出的测试项目和测试方法比较了每个实验的样品。研究结果表明,负载精油的纳米纤维垫将成为未来用于不同生物医学应用的有前途的材料。

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