N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia.
All-Russian Research Institute for Phytopathology, B. Vyazyomy, Moscow 143050, Russia.
Molecules. 2020 Apr 22;25(8):1954. doi: 10.3390/molecules25081954.
In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. is a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity of cyclic synthetic peroxides against isolated from L. The peroxides exhibited high mycelium growth inhibition of up to 94-100% at concentration 30 mg/L. EC values were determined for the most active peroxides. Two peroxides showed higher antifungal activity against than the commercial fungicide Triadimefon. The studied peroxides did not reduce the ability of bumblebees to fly and did not lead to the death of bumblebees. A new field of application for peroxides was disclosed.
近年来，世界上的传粉媒介数量明显减少。造成这种情况的一个可能原因是农用化学品的毒性影响降低了昆虫的免疫力，导致它们更容易受到病原体的侵害。Nosema ceranae 是一种危险的昆虫病原真菌，会感染蜜蜂和熊蜂。我们研究了环状合成过氧化物对从 L. 分离出的 N. ceranae 的杀真菌活性。过氧化物在浓度为 30mg/L 时对菌丝体生长的抑制率高达 94-100%。还测定了最活跃的过氧化物的 EC 值。两种过氧化物对 N. ceranae 的抗真菌活性均高于商业杀真菌剂 Triadimefon。研究用的过氧化物不会降低熊蜂的飞行能力，也不会导致熊蜂死亡。过氧化物开辟了一个新的应用领域。
