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[心脏胆碱能神经丛的结构及其在心脏性猝死中的作用]

[Structure of the cholinergic nerve plexuses of the heart and their function in sudden cardiac death].

作者信息

Zhuchkova N I

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1988;11(2):54-8.

PMID:3233155
Abstract

54 hearts of men aged 30-60 were studied histochemically. The control consisted of 12 hearts of persons who died of cerebral injury. 42 persons died suddenly by fresh myocardial infarction, small-focal cardiosclerosis, postinfarction cardiosclerosis or alcohol cardiomyopathy. The density of nervous plexus was higher in the right atrium than in the left one. Right and left ventricle differed in the same way. In older persons, especially those who died suddenly, density of myocardial cholinergic nervous plexus (especially perivasal) decreased which was associated with development of perivasal fibrosis characteristic for neurotomy of perivasal plexus. Density of cardiac cholinergic plexus differed in various myocardial pathologies. It was the highest in sudden death in patients with small-focal cardiosclerosis and the lowest in sudden death in patients with fresh myocardial infarction.

摘要

对54例年龄在30至60岁男性的心脏进行了组织化学研究。对照组由12例死于脑损伤者的心脏组成。42例因新鲜心肌梗死、小灶性心肌硬化、梗死后心肌硬化或酒精性心肌病而突然死亡。右心房神经丛密度高于左心房。左右心室情况相同。在老年人中,尤其是那些突然死亡者,心肌胆碱能神经丛(尤其是血管周围的)密度降低,这与血管周围神经丛切断术特有的血管周围纤维化发展有关。心脏胆碱能神经丛密度在各种心肌病变中有所不同。在小灶性心肌硬化患者的猝死中最高,而在新鲜心肌梗死患者的猝死中最低。

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