From the Department of Nuclear Medicine, Affiliated Hospital of Southwest Medical University/Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou.
Department of Radiology, Yibin First People's Hospital, Yibin, Sichuan, People's Republic of China.
Clin Nucl Med. 2020 Jun;45(6):465-467. doi: 10.1097/RLU.0000000000003039.
A 51-year-old man with 30-year neurofibromatosis and 2-month elevated prostate-specific antigen and back pain underwent a Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for possible prostate cancer. Prostate-specific membrane antigen PET/CT imaging showed no abnormal uptake of the prostate. However, in addition to PSMA uptake in his left lung, thorax, and right ilium, which was confirmed being a lung squamous cell carcinoma by a lung biopsy, widespread uptake was also observed in his skin fibroma lesions. This case demonstrates that benign neurofibromatosis could have uptake of PSMA.
一位 51 岁男性，患有神经纤维瘤病 30 年，前列腺特异性抗原升高 2 个月伴背痛，行 Ga-前列腺特异性膜抗原（PSMA）PET/CT 扫描以排除前列腺癌。PSMA PET/CT 显像示前列腺未见异常摄取。然而，除了左肺、胸部和右侧髂骨的 PSMA 摄取（经肺活检证实为肺鳞状细胞癌）外，皮肤纤维瘤病变也广泛摄取。该病例表明良性神经纤维瘤病也可能摄取 PSMA。
