Kim Chul-Hyun, Park Yongbum, Chun Min Young, Kim Young-Joo
Department of Sports Medicine, Soonchunhyang University, Asan.
Department of Rehabilitation Medicine, Sanggye Paik Hospital, Inje University College of Medicine.
Medicine (Baltimore). 2020 Apr;99(17):e19911. doi: 10.1097/MD.0000000000019911.
Marathon runners demonstrate a high incidence of coronary artery plaque; however, studies on runners with exercise-induced hypertension (EIH) are sparse. We aimed to investigate the prevalence of coronary artery plaque among marathon runners with EIH.Veteran male marathon runners (≥40 and <60 years) underwent an exercise stress test. They were divided into 2 groups: normal blood pressure group (NBPG, n = 22), with resting systolic blood pressure (SBP)/diastolic blood pressure <140/90 mm Hg and maximal exercise SBP <210 mm Hg, and EIH group (EIHG, n = 28), with resting blood pressure <140/90 mm Hg and maximal exercise SBP ≥210 mm Hg. Coronary artery plaque and stenosis were compared using multi-detector computed tomography.The proportion of subjects with a coronary artery calcium (CAC) score ≥10 or ≥100 units, 1 or ≥2 plaques, or plaques in ≥2 blood vessels was higher in the EIHG than in the normal blood pressure group (NBPG) (P<.05). The absolute CAC score was higher in the EIHG (42.6 ± 67.8) than in the NBPG (2.8 ± 6.0; P < .05). The CAC score distribution was higher in the EIHG (5-300 units) than in the NBPG (P < .05). The prevalence of coronary plaques and maximal luminal artery stenosis was higher in the EIHG than in the NBPG (P < .05). The EIHG showed 12 cases of stenosis, whereas the NBPG showed only 1 case (P < .05).In marathon runners, EIH was associated with increased prevalence of coronary artery plaques and could be a new risk factor for coronary artery plaque formation. Therefore, preventive measures and EIH monitoring using an exercise stress test, alongside multi-detector computed tomography, are recommended.
马拉松运动员冠状动脉斑块的发生率较高；然而，关于运动性高血压（EIH）跑步者的研究却很少。我们旨在调查患有EIH的马拉松运动员中冠状动脉斑块的患病率。年龄在40至60岁之间的男性资深马拉松运动员接受了运动压力测试。他们被分为两组：正常血压组（NBPG，n = 22），静息收缩压（SBP）/舒张压<140/90 mmHg且最大运动SBP<210 mmHg；以及EIH组（EIHG，n = 28），静息血压<140/90 mmHg且最大运动SBP≥210 mmHg。使用多排螺旋计算机断层扫描比较冠状动脉斑块和狭窄情况。EIH组中冠状动脉钙化（CAC）评分≥10或≥100单位、有1个或≥2个斑块、或≥2支血管中有斑块的受试者比例高于正常血压组（NBPG）（P<.05）。EIH组的绝对CAC评分（42.6±67.8）高于NBPG组（2.8±6.0；P<.05）。EIH组的CAC评分分布（5 - 300单位）高于NBPG组（P<.05）。EIH组冠状动脉斑块和最大管腔动脉狭窄的患病率高于NBPG组（P<.05）。EIH组有12例狭窄，而NBPG组仅有1例（P<.05）。在马拉松运动员中，EIH与冠状动脉斑块患病率增加相关，可能是冠状动脉斑块形成的一个新危险因素。因此，建议采取预防措施，并使用运动压力测试以及多排螺旋计算机断层扫描对EIH进行监测。
