Laboratorio de Toxicología Ambiental, Facultad de Química, Universidad Autónoma del Estado de México, Paseo Colón i2antersección Paseo Tollocan, Colonia Residencial Colón, CP 50120 Toluca, Estado de México, Mexico.
Universidad de las Américas Puebla, Departamento de Ciencias Químico-Biológicas, ExHda. Sta. Catarina Martir s/n, Cholula 72820, Puebla, Mexico.
Sci Total Environ. 2020 Jul 20;727:138716. doi: 10.1016/j.scitotenv.2020.138716. Epub 2020 Apr 15.
Hospitals consume a large amount of water, so they also generate large amounts of wastewater, which contain a wide variety of contaminants. It is important to consider that hospital effluents are a mixture of pollutants that can interact with each other and have a negative impact on aquatic species of water bodies. The aim of this study was to evaluate the effects induced by a hospital effluent using Danio rerio embryos. In this study, Danio rerio embryos were exposed to different concentrations of the hospital effluent and a lethality test was evaluated and the malformations present in zebrafish embryos were evaluated. The lethal concentration of effluent 50% was 6.1% and the effective malformation concentration was of 2.5%. The teratogenic index was 2.45%. The main malformations identified were yolc sac malformation, pericardial edema, hatching abnormalities, hypopigmentation, tail deformation, chorda malformation, without fin, chorion deformation and craniofacial malformation. The risks that this type of water represents for the survival of living organisms, as well as the presence of malformations in them, are reference indicators for a future regulation focused on the adequate treatment of hospital effluents.
医院消耗大量的水，因此也会产生大量的废水，其中含有各种污染物。需要考虑到的是，医院污水是各种污染物的混合物，它们可能相互作用，对水体中的水生生物产生负面影响。本研究旨在评估医院污水对斑马鱼胚胎的影响。在这项研究中，斑马鱼胚胎暴露于不同浓度的医院污水中，并评估了死亡率测试和斑马鱼胚胎中存在的畸形情况。污水的半致死浓度为 6.1%，有效致畸浓度为 2.5%。致畸指数为 2.45%。鉴定的主要畸形包括卵黄囊畸形、心包水肿、孵化异常、色素减退、尾巴变形、脊索畸形、无鳍、绒毛膜变形和颅面畸形。此类水对生物生存的风险，以及其中存在的畸形，是未来关注医院污水适当处理的法规的参考指标。
