Department of Radiology, Research Division, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, 1st Floor, Room 115A, Philadelphia, PA 19104, USA.
Department of Psychology, University of California, Los Angeles, Franz Hall, 502 Portola Plaza, Los Angeles, CA 90095, USA.
Neuroimaging Clin N Am. 2020 May;30(2):205-216. doi: 10.1016/j.nic.2020.01.002. Epub 2020 Apr 9.
Schizophrenia (Sz) is a chronic mental disorder characterized by disturbances in thought (such as delusions and confused thinking), perception (hearing voices), and behavior (lack of motivation). The lifetime prevalence of Sz is between 0.3% and 0.7%, with late adolescence and early adulthood, the peak period for the onset of psychotic symptoms. Causal factors in Sz include environmental and genetic factors and especially their interaction. About 50% of individuals with a diagnosis of Sz have lifelong impairment.
精神分裂症(Sz)是一种慢性精神障碍,其特征是思维紊乱(如妄想和思维混乱)、知觉(幻听)和行为(缺乏动力)紊乱。Sz 的终身患病率在 0.3%至 0.7%之间,青春期后期和成年早期是出现精神病症状的高峰期。Sz 的病因包括环境和遗传因素,特别是它们的相互作用。大约 50%被诊断为 Sz 的个体终生受损。