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翼状胬肉切除联合结膜自体移植术后两种不同方案的术后治疗依从率及并发症比较。

Postoperative treatment compliance rate and complications with two different protocols after pterygium excision and conjunctival autografting.

机构信息

Ophthalmology Service, Institut Clinic d'Oftalmologia (ICOF), Hospital Clinic de Barcelona, Barcelona, Spain.

Ophthalmology Service, Hospital Universitari Sagrat Cor, Barcelona, Spain.

出版信息

Eur J Ophthalmol. 2021 May;31(3):932-937. doi: 10.1177/1120672120917335. Epub 2020 Apr 27.

Abstract

AIM

To evaluate compliance rate to pterygium postoperative treatment with two different protocols.

METHODS

Review of clinical data of patients submitted to pterygium excision and conjunctival autografting in a single centre (and a single surgeon) in Barcelona between March 2014 and December 2017. Initial postoperative protocol (protocol 1) consisted of 4 months of topical steroids in a tapering fashion. Protocol 2 consisted of topical steroids tapered over 5 weeks. Compliance rate, complications and clinical outcomes were evaluated, and statistical comparisons were made.

RESULTS

120 surgeries were performed in 99 patients. Protocol 1 was applied in 63 cases and the next 57 followed protocol 2. Compliance with protocol 1 (57.6%) was lower than with protocol 2 (84.9%) (p = 0.002). Intraoperative complications (graft tear, corneal thinning, corneal perforation and bleeding) were found in 10 cases of protocol 1 and three cases of protocol 2, p = 0.08. Postoperative complications (graft dislocation, graft haematoma, ocular hypertension and recurrence) were found in 31 cases of protocol 1 (46.2%) and eight cases of protocol 2 (14%), p = 0.001. Six weeks after surgery, ocular hypertension was detected in eight cases corresponding to protocol 1 (13.6%) and two cases of protocol 2 (3.8%), p = 0.099. Recurrence rate during first year was higher in protocol 1 (26.3%) compared to protocol 2 (7.6%), p = 0.011. No cases of visual acuity worsening or infection were registered.

CONCLUSION

Protocol 2 has shown to have higher compliance rate than protocol 1 and less postoperative complications, proving to be a safe and effective postoperative treatment after pterygium surgery.

摘要

目的

评估两种不同方案治疗翼状胬肉术后的依从率。

方法

回顾 2014 年 3 月至 2017 年 12 月期间在巴塞罗那的一家中心(和一位外科医生)接受翼状胬肉切除术和结膜自体移植术的患者的临床数据。初始术后方案(方案 1)包括 4 个月的皮质类固醇递减治疗。方案 2 包括 5 周时间的皮质类固醇递减治疗。评估了依从率、并发症和临床结果,并进行了统计学比较。

结果

共对 99 例患者的 120 例手术进行了研究。63 例采用方案 1,57 例采用方案 2。方案 1(57.6%)的依从率低于方案 2(84.9%)(p=0.002)。方案 1 中发现 10 例术中并发症(移植物撕裂、角膜变薄、角膜穿孔和出血)和方案 2 中发现 3 例术中并发症,p=0.08。方案 1 中发现 31 例术后并发症(移植物脱位、移植物血肿、眼压升高和复发)和方案 2 中发现 8 例术后并发症(p=0.001)。术后 6 周,方案 1 中发现 8 例(13.6%)眼压升高,方案 2 中发现 2 例(3.8%)眼压升高,p=0.099。方案 1 中第一年的复发率(26.3%)高于方案 2(7.6%),p=0.011。未发现视力下降或感染病例。

结论

方案 2 显示出比方案 1 更高的依从率和更少的术后并发症,证明其是一种安全有效的翼状胬肉术后治疗方法。

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