Ophthalmology Service, Institut Clinic d'Oftalmologia (ICOF), Hospital Clinic de Barcelona, Barcelona, Spain.
Ophthalmology Service, Hospital Universitari Sagrat Cor, Barcelona, Spain.
Eur J Ophthalmol. 2021 May;31(3):932-937. doi: 10.1177/1120672120917335. Epub 2020 Apr 27.
To evaluate compliance rate to pterygium postoperative treatment with two different protocols.
Review of clinical data of patients submitted to pterygium excision and conjunctival autografting in a single centre (and a single surgeon) in Barcelona between March 2014 and December 2017. Initial postoperative protocol (protocol 1) consisted of 4 months of topical steroids in a tapering fashion. Protocol 2 consisted of topical steroids tapered over 5 weeks. Compliance rate, complications and clinical outcomes were evaluated, and statistical comparisons were made.
120 surgeries were performed in 99 patients. Protocol 1 was applied in 63 cases and the next 57 followed protocol 2. Compliance with protocol 1 (57.6%) was lower than with protocol 2 (84.9%) (p = 0.002). Intraoperative complications (graft tear, corneal thinning, corneal perforation and bleeding) were found in 10 cases of protocol 1 and three cases of protocol 2, p = 0.08. Postoperative complications (graft dislocation, graft haematoma, ocular hypertension and recurrence) were found in 31 cases of protocol 1 (46.2%) and eight cases of protocol 2 (14%), p = 0.001. Six weeks after surgery, ocular hypertension was detected in eight cases corresponding to protocol 1 (13.6%) and two cases of protocol 2 (3.8%), p = 0.099. Recurrence rate during first year was higher in protocol 1 (26.3%) compared to protocol 2 (7.6%), p = 0.011. No cases of visual acuity worsening or infection were registered.
Protocol 2 has shown to have higher compliance rate than protocol 1 and less postoperative complications, proving to be a safe and effective postoperative treatment after pterygium surgery.
评估两种不同方案治疗翼状胬肉术后的依从率。
回顾 2014 年 3 月至 2017 年 12 月期间在巴塞罗那的一家中心(和一位外科医生)接受翼状胬肉切除术和结膜自体移植术的患者的临床数据。初始术后方案(方案 1)包括 4 个月的皮质类固醇递减治疗。方案 2 包括 5 周时间的皮质类固醇递减治疗。评估了依从率、并发症和临床结果,并进行了统计学比较。
共对 99 例患者的 120 例手术进行了研究。63 例采用方案 1,57 例采用方案 2。方案 1(57.6%)的依从率低于方案 2(84.9%)(p=0.002)。方案 1 中发现 10 例术中并发症(移植物撕裂、角膜变薄、角膜穿孔和出血)和方案 2 中发现 3 例术中并发症,p=0.08。方案 1 中发现 31 例术后并发症(移植物脱位、移植物血肿、眼压升高和复发)和方案 2 中发现 8 例术后并发症(p=0.001)。术后 6 周,方案 1 中发现 8 例(13.6%)眼压升高,方案 2 中发现 2 例(3.8%)眼压升高,p=0.099。方案 1 中第一年的复发率(26.3%)高于方案 2(7.6%),p=0.011。未发现视力下降或感染病例。
方案 2 显示出比方案 1 更高的依从率和更少的术后并发症,证明其是一种安全有效的翼状胬肉术后治疗方法。