Nitzan M, Goss D E, Chagne D, Roberts V C
Department of Physics, Jerusalem College of Technology, Israel.
Clin Phys Physiol Meas. 1988 Nov;9(4):347-52. doi: 10.1088/0143-0815/9/4/006.
Measurements of skin blood flow have been made in a group of 34 patients presenting with symptoms of peripheral vascular disease. Of the patients, 18 were non-diabetic and the remainder diabetic. Measurements of blood flow were made using the transient thermal clearance method, and of systolic blood pressure in the dorsalis pedis artery using a CW ultrasonic Doppler blood velocimeter and an occluding cuff. There was no difference in pressure index between the two groups. Neither a linear pressure/flow relationship nor the presence of autoregulation was demonstrated. The derivation of specific vascular resistance (SVR) for the two groups shows that in the diabetic it was 7.07 +/- 2.2, while in the non-diabetic it was 11.12 +/- 3.9. The difference is significant (P less than 0.005) and suggests that measurement of SVR may be useful in the differential diagnosis of vascular disease.
对一组34名有外周血管疾病症状的患者进行了皮肤血流测量。其中18名患者非糖尿病患者，其余为糖尿病患者。使用瞬态热清除法测量血流，使用连续波超声多普勒血流仪和阻塞袖带测量足背动脉的收缩压。两组之间的压力指数没有差异。既未证明存在线性压力/流量关系，也未证明存在自动调节。两组的特定血管阻力（SVR）推导表明，糖尿病患者的SVR为7.07±2.2，而非糖尿病患者为11.12±3.9。差异具有显著性（P<0.005），提示SVR测量可能有助于血管疾病的鉴别诊断。
