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Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic?

作者信息

Gursel Mayda, Gursel Ihsan

机构信息

Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.

Thorlab, Therapeutic Oligodeoxynucleotide Research Laboratory, Department of Molecular Biology and Genetics, Ihsan Dogramaci Bilkent University, Ankara, Turkey.

出版信息

Allergy. 2020 Jul;75(7):1815-1819. doi: 10.1111/all.14345. Epub 2020 Jun 8.

DOI:10.1111/all.14345
PMID:32339299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7267226/
Abstract
摘要

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本文引用的文献

1
BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.BCG 疫苗接种通过诱导与训练有素的免疫相关的细胞因子来保护人类免受实验性病毒感染。
Cell Host Microbe. 2018 Jan 10;23(1):89-100.e5. doi: 10.1016/j.chom.2017.12.010.
2
Trained immunity: a memory for innate host defense.训练免疫：先天宿主防御的记忆。
Cell Host Microbe. 2011 May 19;9(5):355-61. doi: 10.1016/j.chom.2011.04.006.
3
The BCG World Atlas: a database of global BCG vaccination policies and practices.《卡介苗世界地图集：全球卡介苗接种政策和实践数据库》。
PLoS Med. 2011 Mar;8(3):e1001012. doi: 10.1371/journal.pmed.1001012. Epub 2011 Mar 22.
4
Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern.结核分枝杆菌毒力因子分枝菌酸的分子结构决定了所引发的炎症模式。
Eur J Immunol. 2011 Feb;41(2):450-60. doi: 10.1002/eji.201040719. Epub 2010 Dec 29.
5
Mapping the global use of different BCG vaccine strains.绘制全球不同卡介苗菌株使用情况的图谱。
Tuberculosis (Edinb). 2009 Jul;89(4):248-51. doi: 10.1016/j.tube.2009.03.002. Epub 2009 Jun 18.
6
Comparable studies of immunostimulating activities in vitro among Mycobacterium bovis bacillus Calmette-Guérin (BCG) substrains.牛分枝杆菌卡介苗（BCG）各亚菌株体外免疫刺激活性的比较研究。
FEMS Immunol Med Microbiol. 2009 Jul;56(2):116-28. doi: 10.1111/j.1574-695X.2009.00559.x. Epub 2009 Apr 27.
7
Genome plasticity of BCG and impact on vaccine efficacy.卡介苗的基因组可塑性及其对疫苗效力的影响。
Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5596-601. doi: 10.1073/pnas.0700869104. Epub 2007 Mar 19.
8
Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa.常规疫苗接种与儿童生存：西非几内亚比绍的随访研究
BMJ. 2000 Dec 9;321(7274):1435-8. doi: 10.1136/bmj.321.7274.1435.
9
A point mutation in the mma3 gene is responsible for impaired methoxymycolic acid production in Mycobacterium bovis BCG strains obtained after 1927.1927年后获得的卡介苗菌株中，mma3基因的一个点突变导致甲氧基分枝菌酸生成受损。
J Bacteriol. 2000 Jun;182(12):3394-9. doi: 10.1128/JB.182.12.3394-3399.2000.