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光疗在生物制剂时代的作用。

Role of phototherapy in the era of biologics.

作者信息

Torres Angeli Eloise, Lyons Alexis B, Hamzavi Iltefat H, Lim Henry W

机构信息

Manila, Philippines; Photomedicine and Photobiology Unit, Department of Dermatology, Henry Ford Health System, Detroit, Michigan.

Photomedicine and Photobiology Unit, Department of Dermatology, Henry Ford Health System, Detroit, Michigan.

出版信息

J Am Acad Dermatol. 2021 Feb;84(2):479-485. doi: 10.1016/j.jaad.2020.04.095. Epub 2020 Apr 24.

DOI:10.1016/j.jaad.2020.04.095
PMID:32339702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7194984/
Abstract

Phototherapy is a safe and effective treatment for many dermatologic conditions. With the advent of novel biologics and small molecule inhibitors, it is important to critically evaluate the role of phototherapy in dermatology. Surveys have shown that many dermatology residency programs do not dedicate time to teaching residents how to prescribe or administer phototherapy. Limitations of phototherapy include access to a center, time required for treatments, and insurance approval. Home phototherapy, a viable option, is also underused. However, it should be emphasized that modern phototherapy has been in use for over 40 years, has an excellent safety profile, and does not require laboratory monitoring. It can be safely combined with many other treatment modalities, including biologics and small molecule inhibitors. In addition, phototherapy costs significantly less than these novel agents. Dermatologists are the only group of physicians who have the expertise and proper training to deliver this treatment modality to our patients. Therefore, to continue to deliver high-quality, cost-effective care, it is imperative that phototherapy be maintained as an integral part of the dermatology treatment armamentarium.

摘要

光疗是治疗多种皮肤病的一种安全有效的方法。随着新型生物制剂和小分子抑制剂的出现,审慎评估光疗在皮肤病学中的作用很重要。调查显示,许多皮肤科住院医师培训项目并未专门安排时间教授住院医师如何开具或实施光疗。光疗的局限性包括需要前往治疗中心、治疗所需时间以及保险审批。家庭光疗作为一种可行的选择,也未得到充分利用。然而,应该强调的是,现代光疗已经使用了40多年,具有出色的安全性,且无需实验室监测。它可以与许多其他治疗方式安全联合使用,包括生物制剂和小分子抑制剂。此外,光疗的费用明显低于这些新型药物。皮肤科医生是唯一有专业知识和适当培训可为患者提供这种治疗方式的医生群体。因此,为了继续提供高质量、具有成本效益的医疗服务,必须将光疗作为皮肤科治疗手段的一个组成部分保留下来。

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