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光疗与蕈样肉芽肿：有哪些新进展？

Phototherapy and mycosis fungoides: what's new?

作者信息

Iacovelli Paolo, Pacifico Alessia, Mariano Maria, Orsini Diego, D'Arino Andrea, Pigliacelli Flavia

机构信息

Clinical Dermatology Unit, and.

Oncologic and Preventive Dermatology Unit, San Gallicano Dermatological Institute, Rome, Italy.

出版信息

Dermatol Reports. 2023 Oct 17;16(Suppl 2):9830. doi: 10.4081/dr.2023.9830. eCollection 2024 May 7.

DOI:10.4081/dr.2023.9830
PMID:39295876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11406204/
Abstract

The most common cutaneous T-cell lymphoma, mycosis fungoides (MF), is clinically characterized by erythematous-violaceous nodules and erythematous-scaly patches. In the early stages of MF, phototherapy is currently the first line of treatment and plays a significant role. This study aims to review and analyze the various phototherapy options for cutaneous lymphoma.

摘要

最常见的皮肤T细胞淋巴瘤——蕈样肉芽肿（MF），临床上的特征为红斑紫罗兰色结节和红斑鳞屑性斑块。在MF的早期阶段，光疗是目前的一线治疗方法且发挥着重要作用。本研究旨在回顾和分析皮肤淋巴瘤的各种光疗选择。

相似文献

1
Phototherapy and mycosis fungoides: what's new?光疗与蕈样肉芽肿：有哪些新进展？
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2
Nb-UVB and PUVA therapy in treating early stages of Mycosis Fungoides: A single-center cross-sectional study.NB-UVB 和 PUVA 疗法治疗蕈样肉芽肿早期：单中心横断面研究。
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3
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): part II. Prognosis, management, and future directions.原发性皮肤 T 细胞淋巴瘤（蕈样肉芽肿和赛泽里综合征）：第二部分。预后、治疗和未来方向。
J Am Acad Dermatol. 2014 Feb;70(2):223.e1-17; quiz 240-2. doi: 10.1016/j.jaad.2013.08.033.
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Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): part I. Diagnosis: clinical and histopathologic features and new molecular and biologic markers.原发性皮肤 T 细胞淋巴瘤（蕈样肉芽肿和赛泽里综合征）：第一部分。诊断：临床和组织病理学特征以及新的分子和生物学标志物。
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Photodermatol Photoimmunol Photomed. 2024 Jan;40(1):e12938. doi: 10.1111/phpp.12938. Epub 2023 Dec 29.

本文引用的文献

1
Nb-UVB and PUVA therapy in treating early stages of Mycosis Fungoides: A single-center cross-sectional study.NB-UVB 和 PUVA 疗法治疗蕈样肉芽肿早期：单中心横断面研究。
Photodermatol Photoimmunol Photomed. 2023 Sep;39(5):435-440. doi: 10.1111/phpp.12873. Epub 2023 Mar 27.
2
Prognosis in early stage cutaneous T-cell lymphoma treated with psoralen plus ultraviolet A irradiation and low-dose interferon-α: Long-term efficacy and survival according to conventional and emerging clinical endpoints.补骨脂素加紫外线 A 照射和低剂量干扰素-α治疗早期皮肤 T 细胞淋巴瘤的预后：根据传统和新兴临床终点的长期疗效和生存。
Dermatol Ther. 2022 Oct;35(10):e15737. doi: 10.1111/dth.15737. Epub 2022 Aug 9.
3
Efficacy and Safety of Topical Hypericin Photodynamic Therapy for Early-Stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides): The FLASH Phase 3 Randomized Clinical Trial.局部贯叶金丝桃素光动力疗法治疗早期皮肤 T 细胞淋巴瘤（蕈样真菌病）的疗效和安全性：FLASH 阶段 3 随机临床试验。
JAMA Dermatol. 2022 Sep 1;158(9):1031-1039. doi: 10.1001/jamadermatol.2022.2749.
4
The Role of Tumor Microenvironment in the Pathogenesis of Sézary Syndrome.肿瘤微环境在蕈样肉芽肿发病机制中的作用。
Int J Mol Sci. 2022 Jan 15;23(2):936. doi: 10.3390/ijms23020936.
5
The efficacy of 308-nm excimer laser in the treatment of mycosis fungoides.308纳米准分子激光治疗蕈样肉芽肿的疗效
Int J Dermatol. 2023 Feb;62(2):e92-e93. doi: 10.1111/ijd.16050. Epub 2022 Jan 20.
6
The Microenvironment's Role in Mycosis Fungoides and Sézary Syndrome: From Progression to Therapeutic Implications.《蕈样肉芽肿和塞扎里综合征中微环境的作用：从进展到治疗意义》
Cells. 2021 Oct 17;10(10):2780. doi: 10.3390/cells10102780.
7
Phototherapy as a treatment of early-stage mycosis fungoides and predictive factors for disease recurrence: A 17-year retrospective study.光疗作为蕈样肉芽肿早期阶段的一种治疗方法和疾病复发的预测因素：一项长达 17 年的回顾性研究。
Indian J Dermatol Venereol Leprol. 2021 Sep-Oct;87(5):645-650. doi: 10.25259/IJDVL_555_19.
8
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma.T 细胞淋巴瘤突变特征谱揭示了紫外线辐射在皮肤 T 细胞淋巴瘤中的关键作用。
Sci Rep. 2021 Feb 17;11(1):3962. doi: 10.1038/s41598-021-83352-4.
9
Italian expert-based recommendations on the use of photo(chemo)therapy in the management of mycosis fungoides: Results of an e-Delphi consensus.意大利专家关于在蕈样肉芽肿的管理中使用光（化学）疗法的建议：电子德尔菲共识的结果。
Photodermatol Photoimmunol Photomed. 2021 Jul;37(4):334-342. doi: 10.1111/phpp.12658. Epub 2021 Feb 1.
10
Quality of Life, Anxiety, and Depression in Patients With Early-Stage Mycosis Fungoides and the Effect of Oral Psoralen Plus UV-A (PUVA) Photochemotherapy on it.早期蕈样肉芽肿患者的生活质量、焦虑和抑郁以及口服补骨脂素加紫外线A（PUVA）光化学疗法对其的影响。
Front Med (Lausanne). 2020 Aug 5;7:330. doi: 10.3389/fmed.2020.00330. eCollection 2020.