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Old drug repurposing for neglected disease: Pyronaridine as a promising candidate for the treatment of Echinococcus granulosus infections.老药新用治疗被忽视的疾病:Pyronaridine 作为治疗棘球蚴病的有前途的候选药物。
EBioMedicine. 2020 Apr;54:102711. doi: 10.1016/j.ebiom.2020.102711. Epub 2020 Apr 9.
2
Disease burden of echinococcosis in Tibetan communities-A significant public health issue in an underdeveloped region of western China.包虫病在藏区的疾病负担——中国西部欠发达地区的一个重大公共卫生问题。
Acta Trop. 2020 Mar;203:105283. doi: 10.1016/j.actatropica.2019.105283. Epub 2019 Dec 5.
3
Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.将抗疟药 pyronaridine 四磷酸盐重新用于预防埃博拉病毒感染。
PLoS Negl Trop Dis. 2019 Nov 21;13(11):e0007890. doi: 10.1371/journal.pntd.0007890. eCollection 2019 Nov.
4
Control of cystic echinococcosis: Background and prospects.包虫病防治:背景与展望。
Zoonoses Public Health. 2019 Dec;66(8):889-899. doi: 10.1111/zph.12649. Epub 2019 Sep 17.
5
Echinococcosis: Advances in the 21st Century.包虫病:21 世纪的进展。
Clin Microbiol Rev. 2019 Feb 13;32(2). doi: 10.1128/CMR.00075-18. Print 2019 Mar 20.
6
Treatment of echinococcosis: albendazole and mebendazole--what else?棘球蚴病的治疗:阿苯达唑和甲苯达唑——还有其他的吗?
Parasite. 2014;21:70. doi: 10.1051/parasite/2014073. Epub 2014 Dec 22.
7
Review of pyronaridine anti-malarial properties and product characteristics.吡喹酮抗疟特性和产品特征综述。
Malar J. 2012 Aug 9;11:270. doi: 10.1186/1475-2875-11-270.
8
Dose translation from animal to human studies revisited.动物研究与人体研究间剂量转换的再探讨。
FASEB J. 2008 Mar;22(3):659-61. doi: 10.1096/fj.07-9574LSF. Epub 2007 Oct 17.
9
Albendazole in treatment of human cystic echinococcosis: 12 years of experience.阿苯达唑治疗人体囊型棘球蚴病:12年经验
Acta Trop. 1997 Apr 1;64(1-2):79-93. doi: 10.1016/s0001-706x(96)00640-7.

An old drug as a promising new cure for the hard-to-treat echinococcosis.

作者信息

Zhu Guan, Liu Mingyuan

机构信息

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, United States.

Key Laboratory for Zoonosis Research, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun, China.

出版信息

EBioMedicine. 2020 May;55:102749. doi: 10.1016/j.ebiom.2020.102749. Epub 2020 Apr 24.

DOI:10.1016/j.ebiom.2020.102749
PMID:32339935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7184152/
Abstract
摘要