Fukushima Y, Pikkarainen T, Kallunki T, Eddy R L, Byers M G, Haley L L, Henry W M, Tryggvason K, Shows T B
Department of Human Genetics, Roswell Park Memorial Institute, New York State Department of Health, NY 14263.
Cytogenet Cell Genet. 1988;48(3):137-41. doi: 10.1159/000132610.
Laminin B2 is one of the three polypeptide chains of laminin, a large, complex glycoprotein synthesized by a variety of cells and specifically deposited in basement membranes. A cloned cDNA that encodes the human laminin B2 chain was isolated and characterized. The human laminin B2 gene (LAMB2) was assigned to region 1q25----q31 by (1) hybridization of the probe to DNA from a panel of human x mouse somatic cell hybrids containing different human chromosomes and (2) in situ hybridization to isolated metaphase chromosomes.
