人层粘连蛋白 B1 链 cDNA 克隆的分离及其基因定位
Isolation of a cDNA clone for the human laminin-B1 chain and its gene localization.
作者信息
Jaye M, Modi W S, Ricca G A, Mudd R, Chiu I M, O'Brien S J, Drohan W N
机构信息
Division of Molecular Biology, Rorer Biotechnology, Inc., Springfield, VA 22151.
出版信息
Am J Hum Genet. 1987 Oct;41(4):605-15.
Abstract
A cDNA clone encoding the B1 chain of human laminin has been isolated from a human endothelial cell cDNA library. With use of this probe and a panel of rodent/human somatic-cell hybrids and in situ hybridization, the gene for the human laminin-B1 chain has been localized to chromosome 7, band q31.
摘要
从人内皮细胞cDNA文库中分离出了一个编码人层粘连蛋白B1链的cDNA克隆。利用该探针以及一组啮齿动物/人类体细胞杂种和原位杂交技术，已将人层粘连蛋白B1链基因定位到7号染色体q31带。
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