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在门诊环境中使用即时超声检测到的床边肾细胞癌病例系列。

Case Series of Bedside Renal Cell Carcinoma Detected by Point-of-Care Ultrasound in the Ambulatory Setting.

机构信息

Cedars Sinai Medical Center, Los Angeles, CA, USA.

Cedars Sinai Smidt Heart Institute, Los Angeles, CA, USA.

出版信息

J Prim Care Community Health. 2020 Jan-Dec;11:2150132720916279. doi: 10.1177/2150132720916279.

Abstract

Kidney and renal pelvic cancer was the sixth most common cancer in men and 10th most common in women in the United States in 2018. Renal cell carcinoma (RCC), accounts for 86% of malignancies of the kidney. RCC patients are often asymptomatic; up to 25-30% have metastases at diagnosis. Few present with the triad of gross hematuria, flank pain, and abdominal mass. In RCC patients, 36% had 2 symptoms of the triad, and 60% had gross hematuria as 1 symptom. Point-of-care ultrasound (POCUS) offers a way to identify clinically meaningful anatomic abnormalities. This case series presents 3 patients in whom routine POCUS examination performed in an outpatient cardiology clinic found asymptomatic renal masses, resulting in surgical resection and cure of early-stage RCCs. Patient 1: 54-year-old female with hypertension (HTN). Two solid masses were identified with POCUS in the right kidney. Patient 2: 63-year-old male with coronary artery disease (CAD) and HTN was seen at an 8-month follow-up visit. A 6-cm mass was identified in the left kidney. Patient 3: 69-year-old male with CAD, HTN, and smoking history seen at 5-month follow-up visit. A 3-cm mass in the right kidney was identified. Incorporating POCUS into the routine physical examination in the ambulatory care setting may improve rates of detection and increase the pretest probability of identifying renal pathology with formal imaging studies. With minimal clinician training, earlier and increased detection of asymptomatic RCC may result in improved patient survival.

摘要

2018 年,在美国,肾脏和肾盂癌是男性中第六种最常见的癌症,也是女性中第十种最常见的癌症。肾细胞癌(RCC)占肾脏恶性肿瘤的 86%。RCC 患者通常无症状;多达 25-30%的患者在诊断时已发生转移。很少有患者出现肉眼血尿、腰痛和腹部肿块三联征。在 RCC 患者中,36%有三联征的 2 个症状,60%有肉眼血尿作为 1 个症状。即时护理超声(POCUS)提供了一种识别具有临床意义的解剖异常的方法。本病例系列介绍了 3 例患者,他们在门诊心脏病学诊所进行的常规 POCUS 检查发现了无症状的肾肿块,导致了早期 RCC 的手术切除和治愈。

患者 1:54 岁女性,患有高血压(HTN)。POCUS 在右肾中发现了两个实性肿块。

患者 2:63 岁男性,患有冠状动脉疾病(CAD)和 HTN,在 8 个月的随访就诊时,在左肾中发现了一个 6 厘米大的肿块。

患者 3:69 岁男性,患有 CAD、HTN 和吸烟史,在 5 个月的随访就诊时,在右肾中发现了一个 3 厘米大的肿块。

在门诊环境中,将 POCUS 纳入常规体格检查可能会提高检测率,并增加通过正式影像学研究识别肾脏病理的术前概率。通过最小的临床医生培训,早期和增加无症状 RCC 的检测可能会提高患者的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a1/7232876/b0302a9ff756/10.1177_2150132720916279-fig1.jpg

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