轴性银屑病关节炎：一种寻求定义的独特临床实体。

Axial Psoriatic Arthritis: A Distinct Clinical Entity in Search of a Definition.

作者信息

Michelena Xabier, Poddubnyy Denis, Marzo-Ortega Helena

机构信息

NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Second Floor, Chapeltown Road, Leeds LS7 4SA, UK; Hospital Universitari de Bellvitge-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12203, Germany; German Rheumatism Research Centre, Berlin, Germany.

出版信息

Rheum Dis Clin North Am. 2020 May;46(2):327-341. doi: 10.1016/j.rdc.2020.01.009.

DOI:10.1016/j.rdc.2020.01.009

PMID:32340705

Abstract

Axial involvement in psoriatic arthritis is a well-recognized manifestation with a prevalence between 12.5% and 78%. This huge heterogeneity is due to the different criteria used by authors to define psoriatic arthritis with axial involvement combining clinical features with radiographic evidence of disease. Specific genetic and clinical attributes of axial psoriatic arthritis might differentiate it from axial spondyloarthritis with concurrent skin psoriasis. Few studies address the specific management. The purpose of this review is to acknowledge the current understanding of axial involvement in psoriatic arthritis and highlight the need for a definition to facilitate research and clinical recognition.

摘要

银屑病关节炎的轴向受累是一种公认的表现，患病率在12.5%至78%之间。这种巨大的异质性是由于作者使用不同的标准来定义伴有轴向受累的银屑病关节炎，这些标准将临床特征与疾病的影像学证据相结合。轴向型银屑病关节炎的特定遗传和临床特征可能使其与并发皮肤银屑病的轴向型脊柱关节炎有所区别。很少有研究涉及具体的管理方法。本综述的目的是认识目前对银屑病关节炎轴向受累的理解，并强调需要一个定义以促进研究和临床识别。