Cugini P, Girelli I, Latini M, Cogliati A A, Di Palma L, Battisti P, Felici W, Tucciarone L
Fisiopatologia Endocrina (Unità Cronobiologica), Università degli Studi di Roma La Sapienza, Italy.
Chronobiologia. 1988 Oct-Dec;15(4):291-8.
Chronobiology, in its methodological evolution, developed data series analyses paying particular attention to blood pressure (BP), because of the importance of this biorhythmic variable for assessing the risk of developing hypertension. An example of the potentiality of the chronobiologic procedures is given in the present report which deals with the inferential analysis of the BP 24-h patterns in 3-12 year-old children. By using the chronobiologic methodology, time-qualified standards for BP are calculated. Rhythmometric parameters for circadian rhythm of systolic and diastolic components of BP are also computed. Data presented are a tangible outcome for emphasizing the introduction of chronobiology in epidemiology and pediatrics in order to optimize the primary prevention and care of hypertension taking as reference the chronobiologic standards of BP.
时间生物学在其方法学的发展过程中，开展了数据序列分析，特别关注血压（BP），因为这个生物节律变量对于评估高血压发病风险具有重要意义。本报告给出了一个时间生物学程序潜力的实例，该报告涉及对3至12岁儿童24小时血压模式的推断性分析。通过使用时间生物学方法，计算出了有时间限定的血压标准。还计算了血压收缩压和舒张压成分昼夜节律的节律测量参数。所呈现的数据是一个切实的成果，强调了将时间生物学引入流行病学和儿科学，以便以血压的时间生物学标准为参考，优化高血压的一级预防和护理。
