Cabrera-Rego Julio Oscar, Rojas-Quiroz Andrés Fernando, Vidal-Turruelles Yaumet, Yanes-Quintana Alberto Antonio
Unidad de Cuidados Coronarios Intensivos, Hospital Manuel Fajardo, La Habana, Cuba.
Servicio de Medicina Interna, Hospital Manuel Fajardo, La Habana, Cuba.
Enferm Infecc Microbiol Clin (Engl Ed). 2021 Mar;39(3):115-118. doi: 10.1016/j.eimc.2020.02.032. Epub 2020 Apr 25.
Cardiac complications in dengue patients are not uncommon and are not diagnosed, since they are usually mild and self-limiting.
To characterize the cardiovascular manifestations in hospitalized patients with dengue infection.
We conducted an observational, analytical, longitudinal, prospective epidemiological study, which included 427 patients treated at Manuel Fajardo Clinical-Surgical Teaching Hospital with diagnosis of dengue infection since April 2017 to April 2018.
Cardiovascular manifestations (19.7%), mainly heart rate disorders (sinus bradycardia [13.8%], atrial [4.9%] and ventricular [4.0%] extrasystoles) were frequent in dengue infection patients. Pericarditis and myocarditis were diagnosed in 1.6% and 0.2% respectively. These disorders were self-limiting in 83.3% of cases and occurred in the first days of the onset of fever in 75.0%. Advanced age (OR=1.70), male sex (OR=1.94), decreased platelet count (OR=1.13) and dengue with warning signs (OR=3.29) were related to a higher probability of presenting cardiovascular disorders in the course of a dengue infection.
Cardiovascular manifestations in dengue patients are frequent, and are related to advanced age, male sex, as well as severe forms of the disease.
登革热患者出现心脏并发症并不罕见,但由于通常症状较轻且具有自限性,所以未被诊断出来。
描述登革热感染住院患者的心血管表现。
我们进行了一项观察性、分析性、纵向、前瞻性流行病学研究,研究对象包括2017年4月至2018年4月在曼努埃尔·法哈多临床外科教学医院接受治疗且诊断为登革热感染的427名患者。
心血管表现(19.7%)在登革热感染患者中很常见,主要是心率紊乱(窦性心动过缓[13.8%]、房性[4.9%]和室性[4.0%]期前收缩)。心包炎和心肌炎的诊断率分别为1.6%和0.2%。这些病症在83.3%的病例中具有自限性,75.0%发生在发热开始的头几天。高龄(比值比=1.70)、男性(比值比=1.94)、血小板计数降低(比值比=1.13)以及有警示标志的登革热(比值比=3.29)与登革热感染过程中出现心血管病症的较高概率相关。
登革热患者的心血管表现很常见,且与高龄、男性以及疾病的严重形式有关。