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持续性呃逆作为 COVID-19 的非典型表现。

Persistent hiccups as an atypical presenting complaint of COVID-19.

机构信息

Department of Emergency Medicine, Cook County Health, 1950 W Polk Street, Chicago, IL 60612, USA.

出版信息

Am J Emerg Med. 2020 Jul;38(7):1546.e5-1546.e6. doi: 10.1016/j.ajem.2020.04.045. Epub 2020 Apr 18.

DOI:10.1016/j.ajem.2020.04.045
PMID:32345563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7165082/
Abstract

Hiccups (singultus) are reflex inspiratory movements that involve the swallowing reflex arc and can be classified as acute (<48 h) or persistent (>48 h). A 62-year-old man with no history of malignancy or pulmonary disease presented to the Emergency Department with a four-day history of persistent hiccups. Other than episodic hiccupping, his physical examination was otherwise unremarkable. An abnormal chest X-ray led to a CT scan of the chest with IV contrast, which demonstrated regional, peripheral groundglass opacities of the upper lobes with small focal groundglass opacities scattered throughout the lungs. He was tested for COVID-19 per admission protocol, started on hydroxychloroquine, his hiccups improved, and he was discharged to home after 3 days. An emergency medicine physician should keep COVID-19 on the differential and be vigilant of exposure in atypical presentations.

摘要

呃逆(打嗝)是一种涉及吞咽反射弧的反射性吸气运动,可以分为急性(<48 小时)或持续性(>48 小时)。一名 62 岁男性,无恶性肿瘤或肺部疾病史,因持续性呃逆 4 天就诊于急诊科。除间歇性呃逆外,其体格检查无其他异常。异常的胸部 X 线片导致胸部 CT 扫描加静脉造影,显示上叶区域性、外周磨玻璃样混浊,肺部散布小灶性磨玻璃样混浊。根据入院方案,他接受了 COVID-19 检测,开始服用羟氯喹,呃逆改善,3 天后出院回家。急诊医生应将 COVID-19 列入鉴别诊断,并警惕在非典型表现中的接触。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/c21032a50cac/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/e7d0401c4ee0/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/86407cc5d97b/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/c21032a50cac/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/e7d0401c4ee0/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/86407cc5d97b/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c0a/7165082/c21032a50cac/gr3_lrg.jpg

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本文引用的文献

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JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
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Prolonged Intractable Hiccups Associated with HSV (I&II) Esophagitis and Gastritis.与单纯疱疹病毒(I型和II型)食管炎和胃炎相关的持续性顽固性呃逆
Case Rep Infect Dis. 2023 Feb 28;2023:3561895. doi: 10.1155/2023/3561895. eCollection 2023.
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COVID-19 presenting with persistent hiccup and myocardial infarction in a peritoneal dialysis patient: A case report.一名腹膜透析患者出现持续性呃逆和心肌梗死的新型冠状病毒肺炎病例报告
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Ann Med Surg (Lond). 2022 Aug;80:104312. doi: 10.1016/j.amsu.2022.104312. Epub 2022 Aug 4.
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Association of hiccup and SARS-CoV-2 infection with the administration of dexamethasone: a case report.呃逆与SARS-CoV-2感染及地塞米松使用的关联:一例病例报告。
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[Hiccup].[打嗝声]
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