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肾脏支持治疗中的处方开具。

Prescribing in renal supportive care.

作者信息

Li Kelly, Brown Mark

机构信息

Renal Medicine, St George Hospital, Sydney.

Renal Medicine, University of NSW, Sydney.

出版信息

Aust Prescr. 2020 Apr;43(2):57-60. doi: 10.18773/austprescr.2020.004. Epub 2020 Apr 1.

DOI:10.18773/austprescr.2020.004
PMID:32346212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7186271/
Abstract

Renal supportive care incorporates the principles of palliative care into the management of patients with advanced kidney disease. Its focus is on improving the quality of life for patients with a high burden of symptoms Common problems include pain, restless legs syndrome and uraemic pruritus. Symptom management must involve patient participation, education and non-pharmacological strategies to address both physical and psychosocial problems, and to prioritise patient-centred goals The patients are medically complex and polypharmacy is common. When prescribing, it is important to consider the altered pharmacokinetics, potential drug interactions and the clearance of drugs by dialysis

摘要

肾脏支持性护理将姑息治疗原则纳入晚期肾病患者的管理中。其重点是改善症状负担较重患者的生活质量。常见问题包括疼痛、不安腿综合征和尿毒症瘙痒。症状管理必须让患者参与其中,进行教育并采用非药物策略来解决身体和心理社会问题,并优先考虑以患者为中心的目标。这些患者病情复杂,多重用药很常见。开药时,重要的是要考虑到药代动力学的改变、潜在的药物相互作用以及透析对药物的清除作用。

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本文引用的文献

1
Recommendations for the Care of Patients Receiving Conservative Kidney Management: Focus on Management of CKD and Symptoms.接受保守肾脏管理的患者的护理建议:重点关注 CKD 和症状的管理。
Clin J Am Soc Nephrol. 2019 Apr 5;14(4):626-634. doi: 10.2215/CJN.10510917. Epub 2019 Feb 28.
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Aerobic vs. resistance exercise for chronic non-specific low back pain: A systematic review and meta-analysis.有氧运动与抗阻运动治疗慢性非特异性下腰痛:一项系统评价与荟萃分析。
J Back Musculoskelet Rehabil. 2018;31(5):889-899. doi: 10.3233/BMR-170920.
3
Treatment of Uremic Pruritus: A Systematic Review.尿毒症瘙痒的治疗:系统评价。
Am J Kidney Dis. 2017 Nov;70(5):638-655. doi: 10.1053/j.ajkd.2017.05.018. Epub 2017 Jul 15.
4
Sleep Disorders, Restless Legs Syndrome, and Uremic Pruritus: Diagnosis and Treatment of Common Symptoms in Dialysis Patients.睡眠障碍、不宁腿综合征与尿毒症瘙痒:透析患者常见症状的诊断与治疗
Am J Kidney Dis. 2017 Jan;69(1):117-128. doi: 10.1053/j.ajkd.2016.07.031. Epub 2016 Sep 29.
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Gabapentin for uremic pruritus in hemodialysis patients: a qualitative systematic review.加巴喷丁用于血液透析患者的尿毒症瘙痒:一项定性系统评价
Can J Kidney Health Dis. 2016 Mar 28;3:14. doi: 10.1186/s40697-016-0107-8. eCollection 2016.
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Restless Legs Syndrome in Patients With Chronic Kidney Disease.慢性肾病患者的不宁腿综合征
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7
Pain in chronic kidney disease: a scoping review.慢性肾脏病中的疼痛:一项范围综述
Semin Dial. 2014 Mar;27(2):188-204. doi: 10.1111/sdi.12196. Epub 2014 Feb 12.
8
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.度洛西汀用于治疗疼痛性神经病变、慢性疼痛或纤维肌痛。
Cochrane Database Syst Rev. 2014 Jan 3;2014(1):CD007115. doi: 10.1002/14651858.CD007115.pub3.
9
Long-term effects of melatonin on quality of life and sleep in haemodialysis patients (Melody study): a randomized controlled trial.褪黑素对血液透析患者生活质量和睡眠的长期影响(旋律研究):一项随机对照试验。
Br J Clin Pharmacol. 2013 Nov;76(5):668-79. doi: 10.1111/bcp.12093.