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睡眠障碍、不宁腿综合征与尿毒症瘙痒:透析患者常见症状的诊断与治疗

Sleep Disorders, Restless Legs Syndrome, and Uremic Pruritus: Diagnosis and Treatment of Common Symptoms in Dialysis Patients.

作者信息

Scherer Jennifer S, Combs Sara A, Brennan Frank

机构信息

Division of Palliative Care, NYU School of Medicine, New York, NY; Division of Nephrology, NYU School of Medicine, New York, NY.

Division of Nephrology, Department of Medicine, VA Eastern Colorado Health Care System, University of Colorado School of Medicine, Denver, CO; Division of Palliative Care, Department of Medicine, VA Eastern Colorado Health Care System, University of Colorado School of Medicine, Denver, CO.

出版信息

Am J Kidney Dis. 2017 Jan;69(1):117-128. doi: 10.1053/j.ajkd.2016.07.031. Epub 2016 Sep 29.

Abstract

Maintenance dialysis patients experience a high burden of physical and emotional symptoms that directly affect their quality of life and health care utilization. In this review, we specifically highlight common troublesome symptoms affecting dialysis patients: insomnia, restless legs syndrome, and uremic pruritus. Epidemiology, pathophysiology, and evidence-based current treatment are reviewed with the goal of providing a guide for diagnosis and treatment. Finally, we identify multiple additional areas of further study needed to improve symptom management in dialysis patients.

摘要

维持性透析患者承受着沉重的身心症状负担,这些症状直接影响他们的生活质量和医疗保健利用率。在本综述中,我们特别强调影响透析患者的常见困扰症状:失眠、不宁腿综合征和尿毒症瘙痒。本文回顾了这些症状的流行病学、病理生理学以及基于证据的当前治疗方法,目的是为诊断和治疗提供指导。最后,我们确定了多个需要进一步研究的其他领域,以改善透析患者的症状管理。

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