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[二维超声心动图在短暂性脑缺血发作患者栓塞性心脏病诊断中的作用]

[Role of two-dimensional echocardiography in the diagnosis of embolic cardiopathy in patients with transient cerebral ischemia attacks].

作者信息

Zuppiroli A, Favilli S, Arfaioli C, Cecchi F, Ciaccheri M, Fratiglioni L, Ginanneschi A, Inzitari D, Italiani G, Nencini P

机构信息

Servizio di Cardiologia, Ospedale di Careggi, Firenze.

出版信息

G Ital Cardiol. 1988 Jul;18(7):592-5.

PMID:3234658
Abstract

Cardiac sources of emboli have been frequently described in patients with Transitory Ischemic Attacks (TIAs). The aim of our study was to assess the value of two-dimensional echocardiography (2D-E) in the investigation for possible cardiac aetiology of TIAs. As an offshoot of a larger epidemiologic study which aimed at determining the period prevalence of TIAs in 6.504 subject(s) of the general population aged between 40-65, fifty subjects with TIA (group A) and 66 controls (group B) were studied. A heart disease was found in 20/50 s. (40%) in group A (coronary artery disease: 5; hypertensive heart disease: 4; mitral valve prolapse: 5; left ventricular aneurysms: 2; aortic valve disease: 2; aortic valve prosthesis: 1; atrial fibrillation: 1) and in 5/66 s. (7.5%) in group B (p less than 0.01) (coronary disease: 2; hypertensive heart disease: 1; mitral valve prolapse: 2). A potential source of emboli was present in 11 s. in group A (22%) and in 2 s. in group B (3%) (p less than 0.01). In 4/50 s. in group A and in 1/66 in group B the diagnosis was obtained by means of 2D-E only, because other clinical signs and ECG data were negative. 2D-E could only confirm the diagnosis in the remaining cases, with no additional information (i.e., no intracavitary masses were seen). In conclusion there is a high prevalence of heart disease in patients with TIA over 40 years of age. A cardiac source of emboli may be suspected in a substantial number of cases. Nevertheless the value of routine 2D-E in disclosing an otherwise undetected source of emboli is rather low.

摘要

短暂性脑缺血发作(TIA)患者的心脏栓子来源已被频繁描述。我们研究的目的是评估二维超声心动图(2D-E)在调查TIA可能的心脏病因方面的价值。作为一项更大的流行病学研究的分支,该研究旨在确定40至65岁普通人群中6504名受试者的TIA期间患病率,对50名TIA患者(A组)和66名对照者(B组)进行了研究。A组中20/50例(40%)发现患有心脏病(冠状动脉疾病:5例;高血压性心脏病:4例;二尖瓣脱垂:5例;左心室动脉瘤:2例;主动脉瓣疾病:2例;主动脉瓣人工瓣膜:1例;心房颤动:1例),B组中5/66例(7.5%)发现患有心脏病(p<0.01)(冠状动脉疾病:2例;高血压性心脏病:1例;二尖瓣脱垂:2例)。A组11例(22%)存在潜在栓子来源,B组2例(3%)存在潜在栓子来源(p<0.01)。A组4/50例和B组1/66例仅通过2D-E获得诊断,因为其他临床体征和心电图数据均为阴性。2D-E仅能在其余病例中证实诊断,无额外信息(即未发现心腔内肿块)。总之,40岁以上TIA患者中心脏病患病率很高。在相当多的病例中可能怀疑有心脏栓子来源。然而,常规2D-E在发现其他未检测到的栓子来源方面的价值相当低。

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