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[辅助检查在栓塞性心脏病诊断和治疗中的作用。关于46例病例的回顾性研究]

[Contribution of complementary examinations in the diagnosis and treatment of emboligenic cardiopathies. Retrospective study apropos of 46 cases].

作者信息

Allard-Latour G, Schlama S, Aubran M, Trigano J A, Juhan C, Torresani J

出版信息

Arch Mal Coeur Vaiss. 1985 Aug;78(8):1249-54.

PMID:3935085
Abstract

The aim of this prospective study was to assess the value of complementary investigations in the diagnosis and follow-up of embolic heart disease. Forty-six patients having presented a systemic embolism cardiac origin underwent a standard work up which included clinical examination, ECG, chest X-ray and 2D echocardiography. Other investigations were carried out in some patients: CT cardiac scan (11 cases), gamma scintigraphy with Indium III labelled platelets (6 cases) and angiocardiography (12 cases). The diagnosis of an embolic cardiac lesion was made after the standard investigations in 82% of cases. The remaining 18% of cases hall had echocardiographic abnormalities and enable the diagnosis of clinically imapparent conditions: mitral valve prolapse, aneurysm of the interatrial septum, valvular calcification and cardiomyopathy. A potentially embolic mass was visualised in 18 patients; 6 valvular vegetations, 12 left atrial or ventricular thrombi. The other specialised radionuclide, angiographic and CT investigations only confirmed the echocardiographic diagnosis of intravavitary thrombosis. These results were confirmed surgically in 19% of cases. This study shows that complementary investigations especially echocardiography, allow diagnosis of latent embolic cardiac lesions, some of which may benefit from surgical treatment. In addition, potentially embolic intracardiac masses may be visualised, so confirming the origin of systemic emboli. When surgery is not indicated, echocardiography is a good method of following up the results of medical treatment in some of these masses.

摘要

这项前瞻性研究的目的是评估辅助检查在栓塞性心脏病诊断及随访中的价值。46例有心脏源性全身栓塞的患者接受了包括临床检查、心电图、胸部X线及二维超声心动图在内的标准检查。部分患者还进行了其他检查:心脏CT扫描(11例)、铟III标记血小板的γ闪烁显像(6例)及心血管造影(12例)。82%的病例经标准检查后作出了栓塞性心脏病变的诊断。其余18%的病例有超声心动图异常,从而得以诊断临床不明显的情况:二尖瓣脱垂、房间隔瘤、瓣膜钙化及心肌病。18例患者可见潜在的栓子;6例瓣膜赘生物,12例左心房或心室血栓。其他专门的放射性核素、血管造影及CT检查仅证实了超声心动图对心腔内血栓形成的诊断。19%的病例经手术证实了这些结果。本研究表明,辅助检查尤其是超声心动图,可诊断潜在的栓塞性心脏病变,其中一些病变可能受益于手术治疗。此外,可显示潜在的心脏内栓子,从而证实全身栓塞的来源。当不适合手术时,超声心动图是随访这些栓子中部分病例内科治疗结果的良好方法。

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