人血清白蛋白介导的对血浆中可溶性淀粉样β肽的时间分辨荧光探针识别。
Human serum albumin-mediated recognition of soluble amyloid-β peptides using a time-resolved luminescent probe in plasma.
机构信息
College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China.
出版信息
Chem Commun (Camb). 2020 Jun 4;56(44):5945-5948. doi: 10.1039/d0cc01384f. Epub 2020 Apr 29.
PMID:32347243
Abstract
A terbium(iii) complex can recognize soluble Aβ in plasma through human serum albumin (HSA)-mediated co-assembly, which can not only circumvent the interference of HSA, but also benefit Aβ enrichment with amplified time-resolved luminescence enhancement.
摘要
一种铽(III)配合物可以通过人血清白蛋白（HSA）介导的共组装来识别血浆中的可溶性 Aβ，这不仅可以避免 HSA 的干扰，还可以有利于 Aβ 的富集，并增强时间分辨荧光增强。
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