Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil.
Department of Municipal Health of Londrina, Londrina, Brazil.
Zoonoses Public Health. 2020 Nov;67(7):760-764. doi: 10.1111/zph.12705. Epub 2020 Apr 29.
Toxoplasmosis is a reportable disease in Brazil. The objective of this study was to investigate a toxoplasmosis outbreak at a research institution in Londrina-PR, Brazil. The outbreak was reported in October 2015; however, the first cases occurred in August 2015. Blood samples were collected from 674 persons at the institution. Samples were collected from soil, water (water tank) and food (vegetables) served in the restaurant. Each participant responded to an epidemiological questionnaire. For the blood samples, a chemiluminescent microparticle immunoassay was performed to detect IgM, IgG and specific IgG avidity antibodies; 10.8% (73/674) had evidence of acute toxoplasmosis. Statistical analysis showed a significant association (p < .001) between acute infection and eating lunch in the restaurant of the institution. Regarding the types of food offered in the restaurant during the period, there was a significant association between consuming raw salad (p < .001) and becoming ill. We conclude that the vegetables or raw vegetables served in the restaurant were probably the source of infection; however, the long period between exposure and case reporting made it difficult to identify the source of transmission.
弓形体病在巴西属于法定报告疾病。本研究旨在调查巴西隆德里纳市某研究机构的一起弓形体病暴发疫情。该起暴发疫情于 2015 年 10 月报告，但首例病例发生于 2015 年 8 月。从该机构采集了 674 人的血样。采集了土壤、水（水箱）和餐厅供应的食物（蔬菜）样本。每位参与者均回答了一份流行病学调查问卷。对血样进行了化学发光微粒子免疫检测，以检测 IgM、IgG 和特异性 IgG 亲和力抗体；73/674 人（10.8%）有急性弓形体病的证据。统计分析显示，急性感染与在机构餐厅吃午餐之间存在显著关联（p<0.001）。关于该机构餐厅在疫情期间提供的食物类型，食用生沙拉与发病之间存在显著关联（p<0.001）。我们得出结论，餐厅供应的蔬菜或生蔬菜可能是感染源；然而，暴露与病例报告之间的时间间隔较长，使得确定传播源变得困难。
